Isoindolines: A new series of potent and selective endothelin-A receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 13, 2001, Pages 1737-1740

  Kukkola, Paivi J ^a   Bilci, Natalie A ^a   Ikler, Theodore ^a   Savage, Paula ^a   Shetty, Suraj S ^a   DelGrande, Dominick ^a   Jeng, Arco Y ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; 3,4 METHYLENEDIOXY ISOINDOLINE DERIVATIVE; 4 (4 METHOXYPHENYL) 2 (3,4 METHYLENEDIOXYPHENYL) 4 OXO 3 (3,4,5 TRIMETHOXYBENZYL) 2 BUTENOIC ACID; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR ANTAGONIST; ISOINDOLE DERIVATIVE; ISOINDOLINE DERIVATIVE; L 749329; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CIS ISOMER; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PHARMACOPHORE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TRANS ISOMER;

INDOLES; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN;

EID: 0035833026     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00273-6     Document Type: Article

References (23)