The first examples of (S)-2-hydroxyacid dehydrogenases catalyzing the transfer of the pro-4S hydrogen of NADH are found in the archaea

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1548, Issue 1, 2001, Pages 169-173

  Graupner, Marion ^a   White, Robert H ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Archaeal malate dehydrogenases; Coenzymes; Enzyme evolution; Pyridine nucleotide stereospecificity

Indexed keywords

2 HYDROXYACID DEHYDROGENASE; 2 OXOACID; ARCHAEAL PROTEIN; HYDROGEN; ISOENZYME; LACTATE DEHYDROGENASE; MALATE DEHYDROGENASE (DECARBOXYLATING); OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; ENZYME SUBSTRATE; METHANOCOCCUS JANNASCHII; METHANOTHERMUS FERVIDUS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTON TRANSPORT; REDUCTION; SEQUENCE HOMOLOGY; STEREOCHEMISTRY; STEREOISOMERISM;

ALCOHOL OXIDOREDUCTASES; ARCHAEA; HYDROGEN; NAD; OXIDATION-REDUCTION; STEREOISOMERISM;

ARCHAEA; METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS; METHANOTHERMUS FERVIDUS;

EID: 0035832782     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(01)00220-5     Document Type: Article

References (29)

1. Stereospecificities of the pyridine nucleotide-linked enzymes
2. Malate dehydrogenase: A model for structure, evolution, and catalysis
3. The stereospecificities of seven dehydrogenases from Acholeplasma laidlawii. The simplest historical model that explains dehydrogenase stereospecificity
4. An evaluation of the substrate specificity and asymmetric synthesis potential of the cloned L-lactate dehydrogenase from Bacillus stearothermophilus
5. Designs for a broad substrate specificity keto acid dehydrogenase
6. L-Lactate dehydrogenase: Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids
7. Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii
8. Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea
9. Two malate dehydrogenases in Methanobacterium thermoautotrophicum
10. Complete genome sequence of Methanobacterium thermoautotrophicum ΔH: Functional analysis and comparative genomics
11. Amino acid sequence homology among the 2-hydroxy acid dehydrogenases: Mitochondrial and cytoplasmic malate dehydrogenases form a homologous system with lactate dehydrogenase
12. Malate dehydrogenase: Distribution, function and properties
13. Properties and primary structure of the L-malate dehydrogenase from the extremely thermophilic archaebacterium Methanothermus fervidus
14. Reaction of phthalate dioxygenase reductase with NADH and NAD: Kinetic and spectral characterization of intermediates
15. The hydride transfer stereospecificity of nicotinamide adenine dinucleotide linked enzymes: A proton magnetic resonance technique
16. 3H]NADPH and the corresponding 4S isomers all with substantial specific activities
17. α-Keto acid chain elongation reactions involved in the biosynthesis of coenzyme B (7-mercaptoheptanoyl threonine phosphate) in methanogenic Archaea
18. Gas-liquid chromatography of trimethylsilyl derivatives of sugars and related substances
19. An inquiry into the source of stereospecificity of lactate dehydrogenase using substrate analogues and molecular modeling
20. 1H-NMR spectroscopy
21. Stereochemistry of hydrogen transfer between pyridine nucleotide and some intermediates of cholesterol catabolism catalyzed by liver alcohol and aldehyde dehydrogenase
22. Purification and properties of 4-hydroxycyclohexanecarboxylate dehydrogenase from Corynebacterium cyclohexanicum
23. Lactate dehydrogenase
24. Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 Å resolution
25. Convergence of active center geometries
26. + nicotinamide but does not experience A-specific hydride transfer
27. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
28. The Alcaligenes eutrophus ldh structural gene encodes a novel type of lactate dehydrogenase