Sequence Requirements for the N-Methyl-D-aspartate Receptor Antagonist Activity of Conantokin-R

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7391-7396

  Blandl, Tamas ^b   Zajicek, Jaroslav ^b   Prorok, Mary ^b   Castellino, Francis J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; BRAIN; SPECTROSCOPY;

PEPTIDES;

BIOCHEMISTRY;

4 CARBOXYGLUTAMIC ACID; ALANINE; CONANTOKIN R; CONANTOKIN T; DIVALENT CATION; DIZOCILPINE; GLUTAMATE RECEPTOR ANTAGONIST; LEUCINE; LYSINE; METAL ION; METHIONINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROLINE; SPERMINE; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR BLOCKING AGENT; ARGININE; CATION; CONANTOKIN-T; CONOTOXIN; MOLLUSC VENOM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PEPTIDE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG ACTIVITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RAT; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; IC 50; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION; SPRAGUE DAWLEY RAT; TEMPERATURE;

ANIMALIA;

1-CARBOXYGLUTAMIC ACID; ALANINE; ANIMALS; ARGININE; CATIONS; CIRCULAR DICHROISM; CONOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; INHIBITORY CONCENTRATION 50; LEUCINE; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; METHIONINE; MICE; MOLLUSK VENOMS; PEPTIDES; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TEMPERATURE;

EID: 0035831553     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006648200     Document Type: Article

References (42)

1. McIntosh, J., Olivera, B. M., Cruz, L., and Gray, W. (1984) J. Biol. Chem. 259, 14343-14346
2. White, H. S., McCabe, R. Y., Armstrong, H., Donevan, S. D., Cruz, L. J., Abogadie, F. C., Torres, J., Rivier, J. E., Paarmann, I., Hollmann, M., and Olivera, B. M. (2000) J. Pharmacol. Exp. Ther. 292, 425-432
3. Haack, J. A., Rivier, J., Parks, T. N., Mena, E. E., Cruz, L. J., and Olivera, B. M. (1990) J. Biol. Chem. 265, 6025-6029
4. Yanagawa, Y., Abe, T., Satake, M., Odani, S., Suzuki, J., and Ishikawa, K. (1988) Biochemistry 27, 6256-6262
5. Nakamura, T., Yu, Z., Fainzilber, M., and Burlingame, A. L. (1996) Protein Sci 5, 524-530
6. Craig, A. G., Jimenez, E. C., Dykert, J., Nielsen, D. B., Gulyas, J., Abogadie, F. C., Porter, J., Rivier, J. E., Cruz, L. J., Olivera, B. M., and McIntosh, J. M. (1997) J. Biol. Chem. 272, 4689-4698
7. Fainzilber, M., Nakamura, T., Lodder, J. C., Zlotkin, E., Kits, K. S., and Burlingame, A. L. (1998) Biochemistry 37, 1470-1477
8. Rigby, A. C., Lucas-Meunier, E., Kalume, D. E., Czerwiec, E., Hambe, B., Dahlqvist, I., Fossier, P., Baux, G., Roepstorff, P., Baleja, J. D., Furie, B. C., Furie, B., and Stenflo, J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 5758-5763
9. Lirazan, M. B., Hooper, D., Corpuz, G. P., Ramilo, C. A., Bandyopadhyay, P., Cruz, L. J., and Olivera, B. M. (2000) Biochemistry 39, 1583-1588
10. Stenflo, J., Ferlund, P., Egan, W., and Roepstorff, P. (1974) Proc. Natl. Acad. Sci. U. S. A. 71, 2730-2733
11. Price, P. A., Otsuka, A. S., Poser, J. W., Kristaponis, J., and Raman, N. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 1447-1451
12. Esmon, C. T., Sadowski, J. A., and Suttie, J. W. (1975) J. Biol. Chem. 250, 4744-4748
13. Wu, S.-M., Morris, D. P., and Stafford, D. W. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2236-2240
14. Wu, S.-M., Cheung, W.-F., Frazier, D., and Stafford, D. W. (1992) Science 254, 1634-1636
15. Rehemtulla, A., Roth, D. A., Wasley, L. C., Kuliopulos, A., Walsh, C. T., Furie, B., Furie, B. C., and Kaufman, R. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4611-4615
16. Roth, D. A., Rehemtulla, A., Kaufman, R. J., Walsh, C. T., Furie, B., and Furie, B. C. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8372-8376
17. Stanley, T. B., Stafford, D. W., Olivera, B. M., and Bandyopadhyay, P. K. (1997) FEBS Lett. 407, 85-88
18. Bandyopadhyay, P. K., Colledge, C. J., Walker, C. S., Zhou, L. M., Hillyard, D. R., and Olivera, B. M. (1998) J. Biol. Chem. 273, 5447-5450
19. Prorok, M., Warder, S. E., Blandl, T., and Castellino, F. J. (1996) Biochemistry 35, 16528-16534
20. Skjaerbaek, N., Nielsen, K. J., Lewis, R. J., Alewood, P., and Craik, D. J. (1997) J. Biol. Chem. 272, 2291-2299
21. Rigby, A. C., Baleja, J. D., Furie, B. C., and Furie, B. (1997) Biochemistry 36, 6906-6914
22. Blandl, T., Zajicek, J., Prorok, M., and Castellino, F. J. (1997) Biochem. J. 328, 777-783
23. Chen, Z. G., Blandl, T., Prorok, M., Warder, S. E., Li, L. P., Zhu, Y., Pedersen, L. G., Ni, F., and Castellino, F. J. (1998) J. Biol. Chem. 273, 16248-16258
24. Warder, S. E., Chen, Z. G., Zhu, Y., Prorok, M., Castellino, F. J., and Ni, F. (1997) FEBS Lett. 411, 19-26
25. Warder, S. E., Prorok, M., Chen, Z. G., Li, L. P., Zhu, Y., Pedersen, L. G., Ni, F., and Castellino, F. J. (1998) J. Biol. Chem. 273, 7512-7522
26. Blandl, T., Warder, S. E., Prorok, M., and Castellino, F. J. (1999) J. Peptide Res. 53, 453-464
27. Blandl, T., Warder, S. E., Prorok, M., and Castellino, F. J. (2000) FEBS Lett. 470, 139-146
28. Mena, E. E., Gullak, M. F., Pagnozzi, M. J., Richter, K. E., Rivier, J., Cruz, L. J., and Olivera, B. M. (1990) Neuroscience Lett. 118, 241-244
29. Hammerland, L. G., Olivera, B. M., and Yoshikami, D. (1992) Eur. J. Pharmacol. 226, 239-244
30. Klein, R. C., Galdzicki, Z., and Castellino, F. J. (1999) Neuropharmacology 38, 1819-1829
31. Skolnick, P., Boje, K., Miller, R., Pennington, M., and Maccecchini, M.-L. (1992) J. Neurochem. 59, 1516-1521
32. Chandler, P., Pennington, M., Maccecchini, M. L., Nashed, N. T., and Skolnick, P. (1993) J. Biol. Chem. 268, 17173-17178
33. Zhou, L.-M., Szendrei, G. I., Fossom, L. H., Maccecchini, M.-L., Skolnick, P., and Otvos, L. (1996) J. Neurochem. 66, 620-628
34. Blandl, T., Prorok, M., and Castellino, F. J. (1998) FEBS Lett. 435, 257-262
35. Nielsen, K. J., Skjaerbaek, N., Dooley, M., Adams, D. A., Mortensen, M., Dodd, P. R., Craik, D. J., Alewood, P. F., and Lewis, R. J. (1999) J. Med. Chem. 42, 415-426
36. Colpitts, T. L., and Castellino, F. J. (1994) Biochemistry 33, 3501-3508
37. Chen, Y.-H., Yang, J. T., and Martinez, H. M. (1972) Biochemistry 11, 4120-4131
38. Griesinger C., Otting G., Wuthrich K., and Ernst R. R. (1988) J. Am. Chem. Soc. 110, 7870-7872
39. Bodenhausen G., Kogler H., and Ernst R. R. (1988) J. Mag. Reson. 58, 370-388
40. States D. I., Haberkorn R. A., and Ruben D. J. (1982) J. Mag. Reson. 48, 286-293
41. Deleted in proof
42. Prorok, M., and Castellino, F. J. (1998) J. Biol. Chem. 273, 19573-19578