Evidence for linkage disequilibrium between the alpha 7-nicotinic receptor gene (CHRNA7) locus and schizophrenia in Azorean families

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 105, Issue 8, 2001, Pages 669-674

  Xu, Junzhe ^a,b   Pato, Michele T ^a,b,c   Torre, Camille Dalla ^a,c   Medeiros, Helena ^a,c   Carvalho, Celia ^a,c   Basile, Vincenzo S ^a,b,c   Bauer, Amy ^a,c   Dourado, Ana ^a,c   Valente, Jose ^a,c   Soares, Maria Joao ^a,b,c   Macedo, Antonio A ^a,b,c   Coelho, Isabel ^a,c   Ferreira, Carlos Paz ^a,b,c   Helena Azevedo, M ^a,c   Macciardi, Fabio ^a,c   Kennedy, James L ^a,b,c   Pato, Carlos N ^a,b,c  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alpha 7 nicotinic receptor; Azores, Portugal; Exon duplication; Genetic linkage; Parent of origin effect; Polymorphism; Schizophrenia

Indexed keywords

NICOTINIC RECEPTOR;

ARTICLE; CHRNA7 GENE; CHROMOSOME 15Q; FAMILY; GENE; GENE DUPLICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; HAPPY PUPPET SYNDROME; HUMAN; MARKER GENE; MEIOSIS; PHENOTYPE; PORTUGAL; PRADER WILLI SYNDROME; PRIORITY JOURNAL; SCHIZOPHRENIA;

ALLELES; AZORES; DNA; FAMILY HEALTH; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; RECEPTORS, NICOTINIC; SCHIZOPHRENIA;

EID: 0035829973     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.1549     Document Type: Article

References (46)

1. Normalization of auditory physiology by cigarette smoking in schizophrenic patients
2. Imprinting and anticipation: Are they relevant to genetic studies of schizophrenia?
3. The Portuguese-language version of the Diagnostic Interview for Genetic Studies
4. A linkage map of human chromosome 15 with an average resolution of 2 cM and containing 55 polymorphic microsatellites
5. Genomic Variation and gene conversion in spinal muscular atrophy: Implications for disease process and clinical phenotype
6. Prader-Willi syndrome and psychoses
7. A generalization of the transmission/disequilibrium test for uncertain haplotype transmission
8. Transmission disequilibrium tests for extended marker haplotypes
9. No evidence for linkage between schizophrenia and markers at chromosome 15q13-14
10. Schizophrenia and smoking an epidemiological survey in a state hospital
11. No evidence for a parent-of-origin effect detected in the pattern of inheritance of schizophrenia
12. Topography of the Duchenne muscular dystrophy (DMD) gene: FIGE and cDNA analysis of 194 cases reveals 115 deletions and 13 duplications
13. Imprint switching on human chromosome 15 may involve alternative transcripts of the SNPPN gene
14. Genome scan of EuropeanAmerican schizophrenia pedigrees: Results of the NIMH Genetics Initiative and Millennium Consortium
15. Imprinting moves to the center
16. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus
17. Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha 7-Nicotinic acetylcholine receptor subunit gene (CHRNA7)
18. Genomic organization and partial duplication of the human 7 neuronal nicotinic acetylcholine receptor gene
19. Progress of genome scan of the NIMH Intramuron schizophrenia collection
20. Anticipation in schizophrenia: New light on a controversial problem
21. Precise localization of human beta-globin gene coplex on chromosome 11
22. Partial gene duplication as a cause of human disease
23. Paternal transmission and anticipation in schizophrenia
24. Anticipation in Japanese families with schizophrenia
25. NIMH genetics initiative millennium schizophrenia consortium: Linkage analysis of African-American pedigrees
26. Angelman syndrome: Three molecular classes identified with chromosome 15qll-ql3-specific DNA markers
27. Family-based tests of association in the presence of linkage
28. Parental imprinting and human disease
29. Duplication of seven exons in the LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia
30. Further investigation of a chromosome 15 locus in schizophrenia: Analysis of affected sibpairs from the NIMH Genetics Initiative
31. A polydiagnostic application of operational criteria in studies of psychotic illness: Development and reliability of the OPCRIT system
32. Anticipation in schizophrenia: A review and consideration
33. Gating of auditory P50 in schizophrenics: Unique effects of clozapine
34. No evidence for linkage of the CHRNA7 gene region in Canadian schizophrenia families
35. Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome
36. Diagnostic interview for genetic studies: Rationale, unique features and training
37. Anticipation and imprinting in schizophrenia
38. Chromosome 11 workshop
39. Selection of homogeneous populations for genetic study: The Portugal Genetics of Psychosis Project
40. Detection of expansion regions in Portuguese bipolar families
41. Haplotype transmission disequilibrium and evidence for linkage of the CHRNA7 gene region to schizophrenia in Southern African Bantu families
42. Support for a chromosome 18p locus conferring susceptibility to functional psychoses in families with schizophrenia, by association and linkage analysis
43. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
44. Further evidence for anticipation in schizophrenia
45. Anticipation and imprinting in Spanish families with schizophrenia
46. Anticipation in mutiplex schizophrenia pedigrees