The acoustic startle response as an effective model for elucidating the effect of genes on the neural mechanism of behavior in mice

Behavioural Brain Research

Volumn 125, Issue 1-2, 2001, Pages 183-188

  Plappert, Claudia F ^a   Pilz, Peter K D ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Amygdala; C57; DBA; Mutant mice; Neuronal mechanisms; Sensitization; Startle; Strain differences

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; AUDITORY STIMULATION; CONFERENCE PAPER; ELECTROSTIMULATION; FEMALE; GENETIC MANIPULATION; MALE; MOUSE; NONHUMAN; PERCEPTIVE THRESHOLD; PONS RETICULAR FORMATION; PRIORITY JOURNAL; SENSITIZATION; SHOCK; SOUND PRESSURE; SPECIES DIFFERENCE; STARTLE REFLEX; SYNAPSE;

AMYGDALA; ANIMALS; AROUSAL; BRAIN; MICE; MICE, INBRED STRAINS; PHENOTYPE; SPECIES SPECIFICITY; STARTLE REACTION; VARIATION (GENETICS);

EID: 0035829376     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(01)00299-6     Document Type: Conference Paper

References (69)

1. Startle disease or hyperekplexia: Further delineation of the syndrome
2. Behavioral characterization of neuropeptide Y knockout mice
3. Link between emotional memory and anxiety states: A study by principal component analysis
4. Conditioned fear as revealed by magnitude of startle response to an auditory stimulus
5. A GLRA1 null mutation in recessive hyperekplexia challenges the functional role of glycine receptors
6. A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death
7. Inbred mouse strains differ in the regulation of startle and prepulse inhibition of the startle response
8. Physiological evidence of exaggerated startle response in a subgroup of vietnam veterans with combat-related PTSD
9. Involvement of subcortical and cortical afferents to the lateral nucleus of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli
10. Intra-amygdaloid infusion of N-methyl-D-aspartate receptor antagonist AP5 blocks acquisition but not expression of fear-potentiated startle to an auditory conditioned stimulus
11. Caudal potine reticular formation of C57BL/6J mice: Responses to startle stimuli, inhibition by tones, and plasticity
12. Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies
13. A multivariate quantitative-genetic analysis of behavioral development in mice
14. Neurotransmission in the rat amygdala related to fear and anxiety
15. Neurobiology of fear responses
16. Sensitization of the acoustic startle reflex by footshocks
17. Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice
18. 5-HT1B receptor modulation of prepulse inhibition: Recent findings in wild-type and 5-HT1B knockout mice
19. Glutamate receptors mediate acoustic input to the reticular brain stem
20. Fear-potentiated startle in two strains of inbred mice
21. Social amnesia in mice lacking the oxytocin gene
22. D2-like dopamine receptor mediation of social-emotional reactivity in a mouse model of anxiety: Strain and experience effects
23. Assessing prepulse inhibition of startle in wild-type and knockout mice
24. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
25. Differences in anxiety-related behaviors and in sensitivity to diazepam in inbred and outbred strains of mice
26. Habituation: A dual process theory
27. Posttraining lesions of the amygdala interfere with fear-potentiated startle to both visual and auditory cconditioned stimuli in C57BL/6J mice
28. Pleiotropic effects of a disrupted K+ channel gene: Reduced body weight, impaired motor skill and muscle contraction, but no seizures
29. Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input
30. From the jumping frenchman of maine to post-traumatic stress disorders: The startle response in neuropsychiatry
31. An overview of neurobiological comparisons in mouse strains
32. Mapping quantitative trait loci for behavioral traits in the mouse
33. Auditory projections from the cochlear nucleus to pontine and mesencephalic reticular nuclei in the rat
34. Deletion of 150 kb in the minimal DiGeorge/velocardiofacial syndrome critical region in mouse
35. The neurobiology of startle
36. Increased startle response in mice carrying mutations of glycine receptor subunit genes
37. Preweanling sensorial and motor development in laboratory mice: Quatitative trait loci mapping
38. A primary acoustic startle pathway: Obligatory role of cochlear root neurons and the reticularis pontis caudalis
39. Social interaction and sensorimotor gating abnormalities in mice lacking Dv11
40. Giant neurons in the caudal pontine reticular formation receive short latency acoustic input: An intracellular recording and HRP-study in the rat
41. Giant neurons in the rat reticular formation: A sensorimotor interface in the elementary acoustic startle circuit?
42. Assessment of locomotor activity, acoustic and tactile startle, and prepulse inhibition of startle in inbred mouse strains and F1 hybrids: Implications of genetic background for single gene and quantitative trait loci analysis
43. Fear-potentiated startle response in mice: Genetic analysis of the C57BL/6J and DBA/2J intercross
44. Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition
45. Sedative but not anxiolytic properties of benzodiazepines are mediated by GABA (A) receptor alpha1 subtype
46. Neuroendocrine function and response to stress in mice with complete disruption of glucagon-like peptide-1 receptor signaling
47. The human glycine receptor beta subunit gene (GLRB): Structure, refined chromosomal localization, and population polymorphism
48. Genetics, haloperidol, and the Fos response in the basal ganglia: A comparison of the C57BL/6J and DBA/2J inbred mouse strains
49. Inbred strain differences in prepulse inhibition of the mouse startle response
50. Alpha 7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: A behavioral characterization of Acra7-deficient mice
51. Impaired learning and memory and altered hippocampal neurodevelopment resulting from interleukin-2 gene deletion
52. The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene in the embryonic inner ear
53. Habituation and sensitization of the acoustic startle response in rats: Amplitude, threshold, and latency measures
54. Interaction between acoustic and electric sensitization of the acoustic startle response in rats
55. Increased sensitization of the acoustic startle response in spasmodic mice with a mutation of the glycine receptor alpha1-subunit gene
56. The dopamine D2, nut not D3 or D4, receptor subtype is essential for prepulse inhibition produced by amphetamine in mice
57. Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha1 subunit of the inhibitory glycine receptor
58. Behavioural reactivity to aversive stimuli in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: Effect of diazepam and FG-7142
59. A missense mutation in the gene encoding alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse
60. Adrenergic alpha2C-receptors modulate the acoustic startle refelx, prepulse inhibition, and aggression in mice
61. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
62. Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease
63. Differences in fear motivated behaviours among inbred mouse strains
64. The superior olivary complex is necessary for the full expression of the acoustic but not tactile startle response in rats
65. Quantitative trait locus analysis of contextual fear conditioning in mice
66. Prolonged exposure to an augmented acoustic environment ameliorates age-related auditory changes in C57BL/6J and DBA/2J mice
67. The BALB/c mouse as an animal model for progressive sensorineural hearing loss
68. Cochlear histopathology of the mutant bustling mouse, BUS/Idr