Irradiation with ultrasound of low output intensity increased chemosensitivity of subcutaneous solid tumors to an anti-cancer agent

Cancer Letters

Volumn 173, Issue 1, 2001, Pages 31-35

  Tomizawa, Minoru ^a,b   Ebara, Masaaki ^a   Saisho, Hiromitsu ^a   Sakiyama, Shigeru ^b   Tagawa, Masatoshi ^b  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA CANCER CENTER   (Japan)

Author keywords

Drug delivery; Electroporation; Gene delivery; Ultrasound

Indexed keywords

BLEOMYCIN; LUCIFERASE; PLASMID DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CHEMOSENSITIVITY; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROPORATION; ENZYME ACTIVITY; GENE TARGETING; GENE TRANSFER; IN VIVO STUDY; INTERMETHOD COMPARISON; LYMPHOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; TUMOR GROWTH; ULTRASOUND THERAPY;

ANIMALS; ANTINEOPLASTIC AGENTS; BLEOMYCIN; CELL DIVISION; COMBINED MODALITY THERAPY; DRUG DELIVERY SYSTEMS; ELECTROPORATION; GENE THERAPY; GENES, REPORTER; LUCIFERASES; LYMPHOMA; MICE; TRANSFECTION; ULTRASONIC THERAPY;

EID: 0035829009     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00687-5     Document Type: Article

References (21)

1. Electrochemotherapy a new antitumor treatment first clinical phase I-II trial
2. Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum (II) in mice
3. Electropermealization of mammalian cells. Quantitative analysis of the phenomenon
4. Enhancement of antitumor effect of bleomycin by low-voltage in vivo electroporation: A study of human uterine leiomyosarcomas in nude mice
5. Antitumor effect of electrochemotherapy on colorectal carcinoma in an orthotopic mouse model
6. Effective treatment of cutaneous and subcutaneous malignant tumours by electroporation
7. In vivo electrically mediated protein and gene transfer in murine melanoma
8. Electrically mediated plasmid DNA delivery to hepatocellular carcinoma in vivo
9. Electroporation-enhanced gene delivery in mammary tumors
10. Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene
11. Induction of cell-membrane porosity by ultrasound
12. Enhanced cytotoxic effect of Ara-C by low intensity ultrasound to HL-60 cells
13. Ultrasound-mediated transdermal protein delivery
14. Ultrasound-mediated transfection of mammalian cells
15. Ultrasound enhances gene expression of liposomal transfection
16. Ultrasound facilitates transduction of naked plasmid DNA into colon carcinoma cells in vitro and in vivo
17. Antitumor effect of PSK at a distant site: Tumor-specific immunity and combination with other chemotherapeutic agents
18. Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration
19. Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium
20. Albumin microbubble echo-contrast material as an enhancer for ultrasound accelerated thrombolysis
21. Echo-enhancing agents: Their physics and pharmacology