TREM-1 in sepsis

Lancet

Volumn 358, Issue 9284, 2001, Pages 776-778

  Cohen, Jonathan ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CD11B ANTIGEN; CD18 ANTIGEN; CELL SURFACE RECEPTOR; CYTOKINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; INTERLEUKIN 1BETA; LIGAND; LIPOPOLYSACCHARIDE; PEPTIDOGLYCAN; POTASSIUM; POTASSIUM CHANNEL; PROTEIN NOD1; PROTEIN TREM1; SCAVENGER RECEPTOR; TOLL LIKE RECEPTOR; TOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CELL CULTURE; CELL NUCLEUS; CELL SURFACE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENETIC TRANSCRIPTION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; IMMUNE RESPONSE; INFLAMMATORY DISEASE; MULTIPLE ORGAN FAILURE; NEUTROPHIL; NOTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PSEUDOMONAS AERUGINOSA; PSORIASIS; RECEPTOR UPREGULATION; SEPSIS; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE SUBPOPULATION;

EID: 0035828402     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(01)06007-X     Document Type: Note

References (20)

1. The pathogenesis of septic shock
2. Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock
3. Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
4. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
5. TREM-1 amplifies inflammation and is a crucial mediator of septic shock
6. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
7. The toll of innate immunity on microbial pathogens
8. Endotoxin opens the Tollgates to innate immunity
9. Toll-like receptors in the induction of the innate immune response
10. The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock
11. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression
12. Neither CD14 nor serumis absolutely necessary for activation of mononuclear phagocytesby bacterial lipopolysaccharide
13. Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria
14. Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact
15. New insights into endotoxin-induced activation of macrophages: Involvement of a K+ channel in transmembrane signaling
16. Human Nod1 confers responsiveness to bacterial lipopolysaccharides
17. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
18. A lipid A analog, E5531, blocks the endotoxin response in human volunteers with experimental endotoxemia
19. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
20. Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family