One-pot direct conversion of 2,3-epoxy alcohols into enantiomerically pure 4-hydroxy-4,5-dihydroisoxazole 2-oxides

Organic Letters

Volumn 3, Issue 5, 2001, Pages 727-729

  Marotta, Emanuela ^a   Micheloni, Laure Marie ^a   Scardovi, Noemi ^a   Righi, Paolo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; ALUMINUM DERIVATIVE; ALUMINUM LITHIUM HYDRIDE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; EPOXIDE; ISOXAZOLE DERIVATIVE; LITHIUM DERIVATIVE;

ARTICLE; CHEMISTRY; CONFORMATION; STEREOISOMERISM; SYNTHESIS;

ALCOHOLS; ALUMINUM COMPOUNDS; EPOXY COMPOUNDS; INDICATORS AND REAGENTS; ISOXAZOLES; LITHIUM COMPOUNDS; MOLECULAR CONFORMATION; STEREOISOMERISM;

EID: 0035826324     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0070379     Document Type: Article

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23. See Supporting Information for full details.
24. 4 ring cleavage, a reduction-elimination of the ester function with concomitant ring opening afforded the corresponding 3-hydroxy nitrile in moderate yields.