Microfabricated reaction and separation systems

Current Opinion in Biotechnology

Volumn 12, Issue 1, 2001, Pages 92-98

  Krishnan, Madhavi ^a   Namasivayam, Vijay ^a   Lin, Rongsheng ^a   Pal, Rohit ^a   Burns, Mark A ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; DNA DETERMINATION; GENE TARGETING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW; RNA ANALYSIS;

EID: 0035823256     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(00)00166-X     Document Type: Review

References (66)

1. Chip-based microsystems for genomic and proteomic analysis
2. Microfabricated electrophoresis chips for simultaneous bioassays of glucose, uric acid, ascorbic acid and acetaminophen
3. Sensing of biological substances based on the bending of microfabricated cantilevers
4. A miniature integrated device for automated multistep genetic assays
5. Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system
6. Micro-microchips: Just how small can we go?
7. Microchip device for cell lysis, multiplex PCR amplification, and electrophoretic sizing
8. Integrated system for rapid PCR-based DNA analysis in microfluidic devices
9. Sanger DNA-sequencing reactions performed in a solid-phase nanoreactor directly coupled to capillary gel electrophoresis
10. Dynamic DNA hybridization on a chip using paramagnetic beads
11. Rapid, high-fidelity analysis of simple sequence repeats on an electronically active DNA microchip
12. Integrated microchip-device for the digestion, separation and postcolumn labeling of proteins and peptides
13. Microchip systems for immunoassay: An integrated immunoreactor with electrophoretic separation for serum theophylline determination
14. Integration of an immunosorbent assay system: Analysis of secretory human immunoglobulin A on polystyrene beads in a microchip
15. Development of binding assays in microfabricated picoliter vials: An assay for biotin
16. The neurochip: A new multielectrode device for stimulating and recording from cultured neurons
17. Surface micropatterning to regulate cell functions
18. Planar chips technology for miniaturisation of separation systems: A developing perspective in chemical monitoring
19. Current developments in electrophoretic and chromatographic separation methods on microfabricated devices
20. Capillary electrophoresis on microchip
21. Microelectrophoresis and auxiliary micromethods
22. Microfabricated devices for genetic diagnostics
23. Recent developments in DNA sequencing by capillary and microdevice electrophoresis
24. Pluronic copolymer liquid crystals: Unique, replaceable media for capillary gel electrophoresis
25. DNA sequencing up to 1300 bases in two hours by capillary electrophoresis with mixed replaceable linear polyacrylamide solution
26. Improvements in DNA sequencing by CE at elevated temperatures using PEO as sieving matrix
27. Capillary electrophoresis in sieving matrices: Selectivity per base, mobility slope and inflection slope
28. On-chip DNA band detection in microfabricated separation systems
29. Electrophoresis of DNA sequencing fragments at elevated temperature in capillaries filled with poly(N-acryloylaminopropanol) gels
30. Eight hundred base sequencing in a microfabricated electrophoretic device
31. DNA sequencing by capillary array electrophoresis and microfabricated array systems
32. Radial capillary array electrophoresis microplate and scanner for high-performance nucleic acid analysis
33. Effects of injector geometry and sample matrix on injection and sample loading in integrated capillary electrophoresis devices
34. Microfabricated porous membrane structures for sample concentration and electrophoretic analysis
35. Optimization of high-speed DNA sequencing on microfabricated capillary electrophoresis channels
36. Turn geometry for minimizing band broadening in microfabricated capillary electrophoresis channels
37. Dispersion sources for compact geometries on microchips
38. Self-sorting of white blood cells in a lattice
39. Sorting biomolecules with microdevices
40. Separation of long DNA molecules in a microfabricated entropic trap array
41. A microfabricated device for sizing and sorting DNA molecules
42. SDS capillary gel electrophoresis of proteins in microfabricated channels
43. Microfluidic diffusion-based separation and detection
44. Plastic microchip electrophoresis with analyte velocity modulation. Application to fluorescence background rejection
45. Detection in capillary electrophoresis
46. Single-molecule detection of DNA separations in microfabricated capillary electrophoresis chips employing focused molecular streams
47. Multichannel mode-filtered light detection based on an optical fiber for small-volume chemical analysis
48. Laser-induced fluorescence detection by liquid core waveguiding applied to DNA sequencing by capillary electrophoresis
49. Improving signal to background ratio for on-the-fly fluorescence lifetime detection in capillary electrophoresis
50. Capillary electrophoresis chips with integrated electrochemical detection
51. Micromachined electrophoresis chips with thick-film electrochemical detectors
52. Electrochemical detection of single-stranded DNA using polymer-modified electrodes
53. Dual-electrode electrochemical detection for poly(dimethylsiloxane)-fabricated capillary electrophoresis microchips
54. Chemiluminescence on microchip
55. Microreactor and electrochemical detectors fabricated using Si and EPON SU-8
56. A micromachined silicon valve driven by a miniature bi-stable electromagnetic actuator
57. Microvalves with bistable buckled polymer diaphragms
58. Nanoliter liquid metering in microchannels using hydrophobic patterns
59. Electroosmotic flow control of fluids on a capillary electrophoresis microdevice using an applied external voltage
60. Miniaturized total analysis systems for biological analysis
61. An integrated nanoliter DNA analysis device
62. Genetic analysis system: Improvements and methods
63. Fabrication of microfluidic systems in poly(dimethylsiloxane)
64. Monolithic microfabricated valves and pumps by multilayer soft lithography
65. Polymer microfabrication methods for microfluidic analytical applications
66. Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping