The upregulation of angiotensin-converting enzyme during neointima formation does not have functional consequences

Life Sciences

Volumn 69, Issue 16, 2001, Pages 1851-1860

  González, Carmen ^b   Gómez, Carmen ^b   Molero, Francisca ^b   Fernández Alfonso, María S ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

AI conversion; Angiotensin converting enzyme; Neointima; Rat carotid artery; Vascular reactivity

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN I; DIPEPTIDYL CARBOXYPEPTIDASE; NITROPRUSSIDE SODIUM; NORADRENALIN; POTASSIUM CHLORIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY INJURY; ARTICLE; BLOOD VESSEL REACTIVITY; COMMON CAROTID ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENZYME ACTIVITY; INTIMA; MALE; NONHUMAN; RAT; RECEPTOR DENSITY; RECEPTOR UPREGULATION; REGULATORY MECHANISM;

ACETYLCHOLINE; ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; CAROTID ARTERY, COMMON; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NITROPRUSSIDE; NOREPINEPHRINE; PEPTIDYL-DIPEPTIDASE A; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; TUNICA INTIMA; UP-REGULATION;

EID: 0035823050     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01265-6     Document Type: Article

References (34)

1. Kinetics of cellular proliferation after arterial injury
2. Restenosis after percutaneous transluminal coronary angioplasty [PTCA]: A report from the PTCA Registry of the National Heart, Lung, and Blood Institute
3. Vascular injury induces angiotensinogen gene expression in the media and neointima
4. Balloon angioplasty enhances the expression of angiotensin II AT1 receptors in the neointima of rat aorta
5. Role of angiotensin subtype 2 receptor in neointima formation after vascular injury
6. Early induction of angiotensin I-converting enzyme in rat carotid artery following balloon injury
7. Induction of angiotensin converting enzyme in the neointima after vascular injury
8. Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury
9. Mechanism[s] of the antiproliferative activity of the angiotensin converting enzyme [ACE] inhibitor spirapril. Modulation by plasma renin activity
10. Effect of ramipril, an inhibitor of angiotensin converting enzyme, on the response of rat thoracic aorta to injury with a balloon catheter
11. Role of angiotensin II in injury-induced neointima formation in rats
12. Prevention of intimal thickenning after endothelial removal by a non-peptide angiotensin II receptor antagonist, losartan
13. Losartan, a nonpeptide angiotensin II [AII] receptor antagonist inhibits neointima formation following balloon injury to rat carotid arteries
14. Angiotensin-converting enzyme inhibitor versus angiotensin II, AT1 receptor antagonist: Effects on smooth muscle cell migration and proliferation after balloon catheter injury
15. Neointima formation after vascular injury is angiotensin II mediated
16. Angiotensin I- converting enzyme
17. Non peptide angiotensin II receptor antagonists
18. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin mediated responses in the rabbit carotid artery
19. Selective muscarinic alterations of nitric oxide-mediated relaxations by neointima
20. Morphologic and functional consequences of intimal hyperplasia in the rat carotid artery
21. The effect of a developing neo-intima on serotonergic contractions
22. Vasoconstrictor responses after neo-intima formation and endothelial removal in the rabbit carotid artery
23. Fluorometric determination of dipeptidyl carboxiopeptidase (angiotensin I converying enzyme)
24. Protein measurement with the Folin phenol reagent
25. Balloon catheter injury to rabbit carotid artery. I. Changes in smooth muscle phenotype
26. Triphasic sequence of neo-intimal formation in the cuffed carotid artery of the rabbit
27. Endothelial regeneration. I. Quantitative analysis of initial stages of endothelial regeneration in rat aortic intima
28. Vascular endothelial growth factor causes endothelial proliferation after vascular injury
29. Repeated endothelial removal augments intimal thickening and attenuates EDRF release
30. Induction of angiotensin converting enzyme in the neointima after vascular injury
31. Evidence for direct local effect of angiotensin in vascular hypertrophy: In vivo gene transfer of ACE
32. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury
33. Angiotensin I-converting enzyme genotype influences arterial response to injury in normotensive rats
34. Modulation of angiotensin-converting enzyme by nitric oxide