Distribution of functional HIV-specific CD8 T lymphocytes between blood and secondary lymphoid organs after 8-18 months of antiretroviral therapy in acutely infected patients

AIDS

Volumn 15, Issue 13, 2001, Pages 1653-1656

  Oxenius, Annette ^a   Yerly, Sabine ^b   Ramirez, Elbe ^b   Phillips, Rodney E ^a   Price, David A ^a   Perrin, Luc ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Antiretroviral therapy; CD8 T lymphocytes; Lymphoid organs; Peripheral blood leukocytes

Indexed keywords

ANTIRETROVIRUS AGENT; CD8 ANTIGEN; DIDANOSINE; LAMIVUDINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL ARTICLE; DRUG EFFECT; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; LYMPHOCYTE COUNT; PRIORITY JOURNAL; VIRUS LOAD;

ANTI-HIV AGENTS; CD8-POSITIVE T-LYMPHOCYTES; DRUG THERAPY, COMBINATION; EPITOPES, T-LYMPHOCYTE; HIV INFECTIONS; HIV-1; HLA ANTIGENS; HUMANS; LEUKOCYTES, MONONUCLEAR; LYMPHOID TISSUE; REVERSE TRANSCRIPTASE INHIBITORS; TIME FACTORS;

EID: 0035822949     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200109070-00007     Document Type: Article

References (7)

1. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes
2. Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy
3. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy
4. Virus burden in lymph nodes and blood of subjects with primary human immunodeficiency virus type 1 infection on bitherapy
5. Decay of cell associated HIV-1 DNA correlates with residual replication in patients treated during acute HIV-1 infection
6. Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection
7. Comparative analysis of cytotoxic T lymphocytes in lymph nodes and peripheral blood of simian immunodeficiency virus-infected rhesus monkeys