Comparison of right and left ventricular responses to left ventricular assist device support in patients with severe heart failure: A primary role of mechanical unloading underlying reverse remodeling

Circulation

Volumn 104, Issue 6, 2001, Pages 670-675

  Barbone, Alessandro ^a   Holmes, Jeff W ^b   Heerdt, Paul M ^c   The', Andrew H S ^c   Naka, Yoshifumni ^a   Joshi, Neel ^a   Daines, Michael ^a   Marks, Andrew R ^a   Oz, Mehmet C ^a   Burkhoff, Daniel ^a  

^a Howard Hughes Medical Institute   (United States)

^b Department of Applied Physics and Applied Mathematics   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Hemodynamics; Mechanics; Remodeling

Indexed keywords

ADULT; ARTICLE; ASSISTED CIRCULATION; CONTROLLED STUDY; FEMALE; HEART ASSIST DEVICE; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART RIGHT VENTRICLE; HEART TRANSPLANTATION; HEART VENTRICLE REMODELING; HEART WORK; HEMODYNAMICS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

EID: 0035822606     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc3101.093903     Document Type: Article

References (25)

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3. Time course of reverse remodeling of the left ventricle during support with a left ventricular assist device
4. Effect of the implantable left ventricular assist device on neuroendocrine activation in heart failure
5. Left ventricular echocardiographic and histologic changes: Impact of chronic unloading by an implantable ventricular assist device
6. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure
7. Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure
8. Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support: A potential mechanism for cardiac recovery
9. PKA phosphorylation dissociates FKBPI2.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
10. Transient normalization of systolic and diastolic function after LVAD support in a patient with dilated cardiomyopathy
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12. Midterm follow-up of patients who underwent removal of a left ventricular assist device after cardiac recovery from end-stage dilated cardiomyopathy
13. Mechanical support in dilated cardiomyopathy: Signs of early left ventricular recovery
14. Comparison of exercise performance in patients with chronic severe heart failure versus left ventricular assist devices
15. Implantable left ventricular assist devices
16. Potential for left ventricular assist devices as outpatient therapy while awaiting transplantation
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18. Improved mortality and rehabilitation of transplant candidates treated with a long-term implantable left ventricular assist device
19. Structural and left ventricular histologic changes after implantable LVAD insertion
20. Gene expression analysis by transcriptional profiling in the left ventricle of patients pre- and post-LVAD support
21. Signaling pathways for cardiac hypertrophy and failure
22. Molecular and cellular mechanisms of myocardial failure
23. Inflow valve regurgitation during LVAD support may interfere with reverse ventricular remodeling
24. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
25. Renin-angiotensin-aldosterone system and myocardial fibrosis