High isolated yields in thermolysin-catalysed synthesis of Z-L-aspartyl-L-phenylalanine methyl ester in toluene at controlled water activity

Tetrahedron Letters

Volumn 42, Issue 19, 2001, Pages 3395-3397

  De Martin, Luigi ^a   Ebert, Cynthia ^a   Gardossi, Lucia ^a   Linda, Paolo ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Aspartame; Organic solvent; Peptide synthesis; Thermodynamically controlled synthesis; Thermolysin; Water activity

Indexed keywords

ASPARTAME; ASPARTYLPHENYLALANINE ETHYL ESTER DERIVATIVE; THERMOLYSIN; TOLUENE; UNCLASSIFIED DRUG; WATER;

ADSORPTION; ARTICLE; CATALYSIS; CHEMICAL REACTION; DEVICE; HYDRATION; PEPTIDE SYNTHESIS; PROTEIN PURIFICATION; REACTION ANALYSIS; THERMODYNAMICS;

EID: 0035821309     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)00452-X     Document Type: Article

References (20)