HIV-1 protease inhibitors may interfere with the ubiquitous intracellular proteases [2]

Annals of Internal Medicine

Volumn 135, Issue 9, 2001, Pages 840-

  Visnegarwala, F ^a   Musher, D M ^a   White A C , Jr ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; ASPARTIC PROTEINASE; CATHEPSIN D; PROTEINASE; PROTEINASE INHIBITOR; UBIQUITIN;

DIABETES MELLITUS; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; INSULIN RESISTANCE; LETTER; LIPOPROTEIN SECRETION; PRIORITY JOURNAL;

EID: 0035818482     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-135-9-200111060-00017     Document Type: Letter

References (5)

1. Severe diabetes associated with protease inhibitor therapy
2. Protease inhibitors do not interfere with prohormone processing
3. Protease inhibitors and adipocyte differentiation in cell culture
4. HIV protease inhibitors increase secretion of apolipoprotein B-lipoproteins from hepatoma cells by preventing proteasomal degradation
5. The mechanism of insulin resistance caused by HIV protease inhibitor therapy