Potential of lectin-N-(2-hydroxypropyl)methacrylamide copolymer-drug conjugates for the treatment of pre-cancerous conditions

Journal of Controlled Release

Volumn 74, Issue 1-3, 2001, Pages 283-293

  Wroblewski S ^a   Berenson, M ^b   Kopeckova P ^a,c   Kopecek J ^a,c  

^a Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Barrett's esophagus; HPMA copolymer lectin drug conjugates; Site specific delivery; Thomsen Friedenreich antigen; Ulcerative colitis

Indexed keywords

ALPHA LACTOSE; AMIDE; ANTIBODY; ANTIGEN; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CELL SURFACE PROTEIN; FLUORESCEIN ISOTHIOCYANATE; LACTOSE; MESOCHLORIN E6; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER LEPTIN; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER PEANUT AGGLUTININ CYCLOSPORIN A; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER PEANUT AGGLUTININ MESOCHLORIN E6; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER WHEAT GERM AGGLUTININ CYCLOSPORIN A; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER WHEAT GERM AGGLUTININ MESOCHLORIN E6; PEANUT AGGLUTININ; THOMSEN FRIEDENREICH ANTIGEN; UNCLASSIFIED DRUG; WHEAT GERM AGGLUTININ;

AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; BARRETT ESOPHAGUS; BINDING AFFINITY; BINDING SITE; CONFERENCE PAPER; CONJUGATE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG TARGETING; GOBLET CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LECTIN BINDING; NEWBORN; NONHUMAN; PRECANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; RAT; ULCERATIVE COLITIS;

ALGORITHMS; ANIMALS; ANIMALS, NEWBORN; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; BARRETT ESOPHAGUS; COLITIS; COLONIC NEOPLASMS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; LECTINS; METHACRYLATES; PEANUT AGGLUTININ; PRECANCEROUS CONDITIONS; RATS; WHEAT GERM AGGLUTININS;

EID: 0035816151     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00338-8     Document Type: Conference Paper

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