Sequential upregulation of cell adhesion molecules in degenerating rat basal forebrain cholinergic neurons and in phagocytotic microglial cells

Brain Research

Volumn 897, Issue 1-2, 2001, Pages 20-26

  Hartlage Rübsamen, Maike ^a   Schliebs, Reinhard ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

192IgG saporin; Cholinergic immunotoxin; ICAM 1; LFS 1; Microglia; Neuronal degeneration

Indexed keywords

CHOLINE ACETYLTRANSFERASE; IMMUNOGLOBULIN G; IMMUNOTOXIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; SAPORIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL LOSS; CELLULAR DISTRIBUTION; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; FOREBRAIN; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; MALE; MICROGLIA; NERVE CELL DEGENERATION; NERVE CELL LESION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; CHOLINERGIC AGENTS; CHOLINERGIC FIBERS; IMMUNOHISTOCHEMISTRY; IMMUNOTOXINS; INJECTIONS, INTRAVENTRICULAR; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MALE; MICROGLIA; N-GLYCOSYL HYDROLASES; NERVE DEGENERATION; PHAGOCYTOSIS; RATS; RATS, WISTAR; SEPTAL NUCLEI; SEPTUM OF BRAIN; UP-REGULATION;

EID: 0035815539     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02093-5     Document Type: Article

References (25)

1. Simulation of cholinergic deficits - A novel experimental approach to study pathogenetic aspects of Alzheimer's disease
2. How LFA-1 binds to different ligands
3. Induction of ICAM-1 on human neural cells and mechanisms of neutrophil-mediated injury
4. Induction of VCAM-1 and ICAM-1 on human neural cells and mechanisms of mononuclear leukocyte adherence
5. Differential adhesion of macrophages to white and grey matter in an in vitro assay
6. Cell adhesion molecules in neural plasticity and pathology: Similar mechanisms, distinct organizations?
7. Adehesion molecule expression on phagocytic microglial cells following anterograde degeneration of perforant path axons
8. Adhesion to human neurons and astrocytes of monocytes: The role of interaction of CR3 and ICAM-1 and modulation by cytokines
9. Normal and abberant functions of integrins in the adult central nervous system
10. Integrin family of cell adhesion molecules in the injured brain: Regulation and cellular localization in the normal and regenerating mouse facial motor nucleus
11. Microglia: A sensor for pathological events in the CNS
12. Adhesion molecule expression and regulation on cells of the central nervous system
13. Interleukin-6 is not expressed in activated microglia and in reactive astrocytes in response to lesion of rat basal forebrain cholinergic system
14. Differential injury-dependent glial expression of interleukins-1α,β and interleukin-6 in rat brain
15. Cell adhesion molecule expression in the regenerating rat facial nucleus
16. 192IgG-saporin immunotoxin-induced loss of cholinergic cells differentially activates microglia in rat basal forebrain nuclei
17. Induction of cellular adehesion molecule-1 on primary and continous cell lines by proinflammatory cytokines
18. Immunolesion by 192IgG-saporin of rat basal forebrain cholinergic system - A useful tool to produce cortical cholinergic dysfunction
19. Electron microscopic evidence for microglial phagocytotic activity and cholinergic cell death after administration of the immunotoxin 192IgG-saporin in rat
20. Differentially displayed genes in neuroblastoma cells treated with a mitochondrial toxin: Evidence for possible involvement of ICAM-1 in 3-nitropropionic acid-mediated neurodegeneration
21. Lymphocyte interactions with endothelial cells
22. Adhesion receptors of the immune system
23. Functional plasticity of microglia: A review
24. Intercellular adhesion molecule-1
25. Differential expression of intercellular adhesion molecule- (ICAM-1) in the Aβ-containing lesions of brains of patients with dementia of the Alzheimer type