Proinflammatory cytokine expression by Theileria annulata infected cell lines correlates with the pathology they cause in vivo

Vaccine

Volumn 19, Issue 20-22, 2001, Pages 2932-2944

  Graham, Simon P ^a,d   Brown, David J ^b   Vatansever, Zati ^a   Waddington, David ^b   Taylor, Louise H ^a   Nichani, Anil K ^a   Campbell, John D M ^a   Adamson, Rachel E ^c   Glass, Elizabeth J ^b   Spooner, Roger L ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

^d INTERNATIONAL LIVESTOCK RESEARCH INSTITUTE   (Kenya)

Author keywords

Pathogenicity; Proinflammatory cytokines; Theileria annulata

Indexed keywords

CYTOKINE; METALLOPROTEINASE; PROTOZOAL VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL PARASITOSIS; ARTICLE; ATTENUATION; CATTLE; CELL CLONE; CONTROLLED STUDY; DISEASE MARKER; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; ENZYME ACTIVITY; INFESTATION; INFLAMMATION; NONHUMAN; PARASITE VIRULENCE; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; THEILERIA ANNULATA;

ANIMALS; CATTLE; CELL LINE; CYTOKINES; IMMUNIZATION; METALLOENDOPEPTIDASES; THEILERIA ANNULATA; THEILERIASIS; VACCINES;

EID: 0035815478     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00529-6     Document Type: Article

References (36)

1. Live vaccines against hemoparasitic diseases in livestock
2. Theileria annulata sporozoite targets
3. Theileria annulata in CD5 macrophages and B1 B-cells
4. Differences between B cell and macrophage transformation by the bovine parasite, Theileria annulata: A clonal approach
5. Cultivation of three species of Theileria in lymphoid cells in vitro
6. Mechanism(s) of attenuation of Theileria annulata vaccine cell lines
7. Directing differentiation in Theileria annulata: Old methods and new possibilities for control of apicomplexan parasites
8. Vaccination of cattle against Theileria annulata using culture-derived schizonts
9. T cell activation by Theileria annulata-infected macrophages correlates with cytokine production
10. Bovine gamma/delta TcR+ T lymphocytes are stimulated to proliferate by autologous Theileria annulata-infected cells in the presence of interleukin-2
11. Theileria annulata induces aberrant T cell activation in vitro and in vivo
12. Macrophages behaving badly: Infected cells and subversion of immune responses to Theileria annulata
13. Effect of chronic administration of recombinant bovine tumor necrosis factor to cattle
14. Malaria parasite-specific Th1-like T cells simultaneously reduce parasitemia and promote disease
15. IL-6-induced anaemia in rats: Possible pathogenic implications for anaemia observed in chronic inflammations
16. Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttoella) vivax and Trypanosoma (Nannomonas) congolense: Possible association with severity of anaemia associated with the disease
17. Control of tropical theileriosis (Theileria annulata infection) of cattle
18. Detection of Theileria annulata in cattle and vector ticks by PCR using Tams1 gene sequences
19. Theileria annulata-infected cells produce abundant proteases whose activity is reduced by long-term cell culture
20. The pathogenesis of anaemia in Theileria annulata infection
21. Absence of erythrocyte forms of Theileria annulata in calves inoculated with schizonts from a virulent field strain grown in tissue culture
22. Tissue damage in cattle infected with Theileria annulata accompanied by metastasis of cytokine-producing, schizont-infected mononuclear phagocytes
23. Cytokines inhibit the development of trophozoite-infected cells of Theileria annulata and Theileria parva but enhance the proliferation of macroschizont-infected cell lines
24. Allograft responses can interfere with the development of immunity against Theileria annulata following vaccination with parasite infected cell lines
25. In vivo development of Theileria annulata: Major changes in efferent lymph following infection with sporozoites or allogeneic schizont-infected mononuclear cells
26. The development and specificity of cytotoxic cells in cattle immunized with autologous or allogeneic Theileria annulata-infected lymphoblastoid cell lines
27. The effect of MHC compatibility between parasite-infected cell line and recipient in immunization against tropical theileriosis
28. A non-protective T helper 1 response against the intra-macrophage protozoan Theileria annulata
29. Phenotypic and genotypic alterations associated with the attenuation of a Theileria annulata vaccine cell line from TUR
30. Theileria annulata: Reduced host MMP activity profile of long-term culture is transmitted as a parasite-encoded trait
31. A role for matrix metalloproteinases in the pathology and attenuation of Theileria annulata infections
32. Influence of host and parasite genotypes on immunological control of Theileria parasites
33. Vaccination against Theileria annulata theileriosis
34. Theileria annulata: Altered gene expression and clonal selection during continuous in vitro culture