Low affinity of β 1 -adrenergic receptor for β-arrestins explains the resistance to agonist-induced internalization

Life Sciences

Volumn 68, Issue 19-20, 2001, Pages 2251-2257

  Shiina, Takako ^a   Nagao, Taku ^a   Kurose, Hitoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Internalization; Arrestin; 1 Adrenergic receptor

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GLUTATHIONE TRANSFERASE; ISOPRENALINE; PHOTOPROTEIN; RETINA S ANTIGEN;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; ENZYME ACTIVITY; IN VITRO STUDY; INTERNALIZATION; PROTEIN LOCALIZATION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; ANIMAL; BINDING SITE; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; INTRACELLULAR MEMBRANE; METABOLISM; PROTEIN TRANSPORT; RAT; ULTRASTRUCTURE;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANIMALS; ARRESTINS; BINDING SITES; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HUMANS; INTRACELLULAR MEMBRANES; ISOPROTERENOL; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; PROTEIN TRANSPORT; RATS; RECEPTORS, ADRENERGIC, BETA-1; RECOMBINANT FUSION PROTEINS;

EID: 0035815076     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01013-X     Document Type: Conference Paper

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