Co-administration of dextromethorphan during pregnancy and throughout lactation significantly decreases the adverse effects associated with chronic morphine administration in rat offspring

Life Sciences

Volumn 69, Issue 20, 2001, Pages 2439-2450

  Tao, Pao Luh ^a   Yeh, Geng Chang ^b   Su, Chia Ho ^a   Wu, Ya Hui ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Adverse effects; Antinociceptive; Dextromethorphan; Morphine; Mortality; N methyl D aspartate; Offspring; Tolerance; Withdrawal

Indexed keywords

DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; DEXTROMETHORPHAN; DIZOCILPINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SODIUM CHLORIDE;

ABDOMEN; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BIRTH WEIGHT; CHRONIC PAIN; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG EFFICACY; FEMALE; HIPPOCAMPUS; LACTATION; MATING; MORPHINE ADDICTION; MORPHINE TOLERANCE; MORTALITY; MUSCLE STRETCHING; NEWBORN; NONHUMAN; PREGNANCY; PROGENY; RAT; RECEPTOR DENSITY; WET DOG SHAKES; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; ANTITUSSIVE AGENTS; BODY WEIGHT; DEXTROMETHORPHAN; DRUG COMBINATIONS; DRUG TOLERANCE; FEMALE; HIPPOCAMPUS; INJECTIONS, SUBCUTANEOUS; LACTATION; LONGEVITY; MALE; MORPHINE; MORPHINE DEPENDENCE; N-METHYLASPARTATE; PAIN MEASUREMENT; PAIN THRESHOLD; PREGNANCY; PREGNANCY, ANIMAL; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY;

CANIS FAMILIARIS;

EID: 0035812774     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01316-9     Document Type: Article

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