The inhibitory effect of the autoantigen La on in vitro 3′ processing of mammalian precursor tRNAs

Journal of Molecular Biology

Volumn 312, Issue 5, 2001, Pages 975-984

  Nashimoto, Masayuki ^a   Nashimoto, Chikako ^a   Tamura, Masato ^b   Kaspar, Roger L ^c   Ochi, Kozo ^a  

^a NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c Brigham Young University   (United States)

Author keywords

3 tRNase; 3 terminal uridine tract; La protein; Pre tRNA; tRNA 3 processing

Indexed keywords

AUTOANTIGEN; AUTOANTIGEN LA; RIBONUCLEASE; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; DISSOCIATION CONSTANT; HUMAN; MAMMAL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN RNA BINDING; RNA ANALYSIS; RNA PROCESSING;

EID: 0035812598     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5026     Document Type: Article

References (26)

1. Genes, variant genes and pseudogenes of the human tRNA(Val) gene family. Expression and pre-tRNA maturation in vitro
2. Ribonucleases, tRNA nucleotidyltransferase, and the 3′ processing of tRNA
3. Conversion of mammalian tRNA 3′ processing endoribonuclease to four-base-recognizing RNA cutters
4. Distribution of both lengths and 5′ terminal nucleotides of mammalian pre-tRNA 3′ trailers reflects properties of 3′ processing endoribonuclease
5. The 3′ end CCA of mature tRNA is an antideterminant for eukaryotic 3′-tRNase
6. Long 5′ leaders inhibit removal of a 3′ trailer from a precursor tRNA by mammalian tRNA 3′ processing endoribonuclease
7. Selection of cleavage site by mammalian tRNA 3′ processing endoribonuclease
8. Anomalous RNA substrates for mammalian tRNA 3′ processing endoribonuclease
9. Minimum requirements for substrates of mammalian tRNA 3′ processing endoribonuclease
10. Characterization of the spermidine-dependent, sequence-specific endoribonuclease that requires transfer RNA for its activity
11. Arg is essential for in vitro specific cleavage of partially synthesized mouse 18S rRNA
12. Specific cleavage of target RNAs from HIV-1 with 5′ half tRNA by mammalian tRNA 3′ processing endoribonuclease
13. RNA heptamers that direct RNA cleavage by mammalian tRNA 3′ processing endoribonuclease
14. Recognition of nascent RNA by the human La antigen: Conserved and divergent features of structure and function
15. Precursor molecules of both human 5 S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies
16. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts
17. The yeast La protein is required for the 3′ endonucleolytic cleavage that matures tRNA precursors
18. 5′ processing of tRNA precursors can be modulated by the human La antigen phosphoprotein
19. Utilizing the C-terminal cleavage activity of a protein splicing element to purify recombinant proteins in a single chromatographic step
20. Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA)
21. Direct interactions between autoantigen La and human immunodeficiency virus leader RNA
22. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate
23. A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein
24. Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes
25. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
26. Site-directed mutagenesis by overlap extension using the polymerase chain reaction