Phosphorylation of threonine 156 of the μ2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo

Current Biology

Volumn 11, Issue 11, 2001, Pages 896-900

  Olusanya, Oyinkan ^a   Andrews, Paul D ^a   Swedlow, Jason R ^a   Smythe, Elizabeth ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035810915     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00240-8     Document Type: Article

References (31)

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4. SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation
5. Multiple GTP binding proteins participate in clathrin-coated vesicle-mediated endocytosis
6. The role of dynamin and its binding partners in coated pit invagination and scission
7. The phosphorylation of coated membrane proteins in intact neurons
8. Clathrin-coated vesicles contain 2 protein-kinase activities - Phosphorylation of clathrin β-light chain by casein kinase-II
9. Internal control of the coated vesicle pp50-specific kinase complex
10. In vivo phosphorylation of adaptors regulates their interaction with clathrin
11. A novel role for rab5-GDI in ligand sequestration into clathrin-coated pits
12. The clathrin coat assembly polypeptide complex - Autophosphorylation and assembly activities
13. The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble ap50 kinase which copurifies with the assembly polypeptides
14. Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities
15. Activation of mitogen-activated protein (MAP) kinase by a MAP kinase-kinase
16. Inhibition of the receptor binding function of clathrin adaptor protein AP-2 by dominant-negative mutant μ2 subunit and its effects on endocytosis
17. 100 kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis
18. Interaction of tyrosine-based sorting signals with clathrin-associated proteins
19. Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes
20. A structural explanation for the recognition of tyrosine-based endocytotic signals
21. Phosphorylation of the medium chain subunit of the AP-2 adaptor complex does not influence its interaction with the tyrosine based internalisation motif of TGN38
22. Binding of AP2 to sorting signals is modulated by AP2 phosphorylation
23. Clathrin functions in the absence of heterotetrameric adaptors and AP180-related proteins in yeast
24. Adaptor complex-independent function in yeast
25. A clathrin binding site in the hinge of the β2 chain of mammalian AP-2 complexes
26. Targeting signals and subunit interactions in coated vesicle adaptor complexes
27. Endocytosis occurs independently of annexin-VI in human A431 cells
28. Purification and characterization of 2 distinct complexes of assembly polypeptides from calf brain coated vesicles that differ in their polypeptide composition and kinase-activities
29. Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431-cells
30. Structural relationships between clathrin assembly proteins from the Golgi and the plasma-membrane