Mutagenicity in Salmonella typhimurium TA98 and TA100 of nitroso and respective hydroxylamine compounds

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 491, Issue 1-2, 2001, Pages 183-193

  Haack, Torsten ^a   Erdinger, Lothar ^b   Boche, Gernot ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Hygieneinstitut Heidelberg   (Germany)

Author keywords

Alkyl substituent; Hydroxylamines; Metabolites; Nitroaromatics; Nitroso compounds; Salmonella

Indexed keywords

2 NITROFLUORENE; 2 NITROSOFLUORENE; 2 NITROSONAPTHALENE; 3 TERT BUTYL 4 HYDROXYLAMINOBIPHENYL; 3 TERT BUTYL 4 NITROBIPHENYL; 3 TERT BUTYL 4 NITROSOBIPHENYL; 4 HYDROXYLAMINOBIPHENYL; 4 NITROBIPHENYL; 4 NITROSOBIPHENYL; 4' TERT BUTYL 4 HYDROXYLAMINOBIPHENYL; 4' TERT BUTYL 4 NITROBIPHENYL; 4' TERT BUTYL 4 NITROSOBIPHENYL; AROMATIC NITRO COMPOUND; HYDROXYLAMINE; N HYDROXY 2 FLUORENYLAMINE; N HYDROXY 2 NAPHTHYLAMINE; NITROSO DERIVATIVE; S 9; UNCLASSIFIED DRUG;

AMES TEST; ARTICLE; CELL INTERACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; METABOLIC ACTIVATION; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SALMONELLA TYPHIMURIUM; STRAIN DIFFERENCE; STRUCTURE ACTIVITY RELATION;

BIOTRANSFORMATION; HYDROXYLAMINES; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENICITY TESTS; MUTAGENS; NITROSO COMPOUNDS; SALMONELLA TYPHIMURIUM;

SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0035810306     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(01)00140-1     Document Type: Article

References (15)

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3. From mutagenic to non-mutagenic nitroarenes: Effect of bulky alkyl substituents on the mutagenic activity of nitroaromatics in Salmonella typhimurium. Part II. Substituents far away from the nitro group
4. Arylamine-DNA adducts in vitro and in vivo: Their role in bacterial mutagenesis and urinary bladder carcinogenesis
5. Formation and persistance of arylamine adducts in vivo
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8. Revised methods for the Salmonella mutagenicity test
9. Synthesis of fluoroaromatic amines
10. The oxidation of some carcinogenic arylhydroxylamines to nitroso derivatives with manganese dioxide
11. 1-Nitrosopyrene: An intermediate in the metabolic activation of 1-nitropyrene to a mutagen in Salmonella typhimurium TA1538
12. Reduction of the carcinogen 1-nitropyrene to 1-aminopyrene by rat intestinal bacteria
13. Mutagenicity of N-hydroxy-2-acetylaminofluorine and N-hydroxyphenacetin and their respective deacetylated metabolites in nitroreductase deficient Salmonella TA98FR and TA100FR
14. Azoxybenzene formation from nitrosobenzene and phenylhydroxlamine: A unified view of the catalysis and mechanisms of the reaction
15. Zirkonium katalysierte oxidation von primären aromatischen aminen zu nitroverbindungen mit tert-butylhydroperoxid