Influence of molecular-level interactions on the orientations of liquid crystals supported on nanostructured surfaces presenting specifically bound proteins

Langmuir

Volumn 17, Issue 18, 2001, Pages 5595-5604

  Skaife, Justin J ^a   Abbott, Nicholas L ^a  

^a University of Wisconsin Madison   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR LEVEL INTERACTIONS;

ANNEALING; DEFECTS; ELASTICITY; ELLIPSOMETRY; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION; NANOSTRUCTURED MATERIALS; ORGANOMETALLICS; PROTEINS; SURFACE TOPOGRAPHY; THIN FILMS;

LIQUID CRYSTALS;

EID: 0035807160     PISSN: 07437463     EISSN: None     Source Type: Journal    
DOI: 10.1021/la010132l     Document Type: Article

References (43)

1. Gupta, V.K.; Skaife, J.J.; Dubrovsky, T.B.; Abbott, N.L. Science 1998, 279, 2077.
2. Skaife, J.J.; Abbott, N.L. Langmuir 2000, 16, 3529.
3. Van Oss, C.J.; van Regenmortel, M.H.V. Immunochemistry; Dekker: New York, 1994.
4. Harlow, E.; Lane, D. Antibodies: A Laboratory Manual; Cold Springs Harbor Laboratory: Cold Springs Harbor, NY, 1988.
5. 8 copies of a protein are typical (refs 3, 4, and 6-9).
6. Steinmetz, I.; Reganzerowski, A.; Brenneke, B.; Haussler, S.; Simpson, A.; White, N.J. J. Clin. Microbiol. 1999, 37, 225.
7. Cocchi, J.M.; Trabaud, M.A.; Grange, J.; Serres, P.F.; Desgranges, C. J. Immunol. Methods 1993, 160, 1.
8. Koertge, T.E.; Butler, J.E. J. Immunol. Methods 1985, 83, 283.
9. Heaton, R.J.; Haris, P.I.; Russel, J.C.; Chapman, D. Biochem. Soc. Trans. 1995, 23, 502s.
10. Schofield, D.J.; Dimmock, N.J. J. Virol. Methods 1996, 62, 33.
11. Marshall, A.; Hodgsan, J. Nat. Biotechnol. 1998, 16, 27.
12. Cheng, J.; Sheldon, E.L.; Wu, L.; Uribe, A.; Gerrue, L.O.; Carrino, J., Heller, M.J.; O'Connell, J.P. Nat. Biotechnol. 1998, 16, 541.
13. Ramsay, G. Nat. Biotechnol. 1998, 16, 40.
14. Shivashankar, G.V.; Libchaber, A. Appl. Phys. Lett. 1998, 73, 417.
15. Fitzgerald, M.C.; Smith, L.M. Annu. Rev. Biophys. Biomol. Struct. 1995, 24, 117.
16. Schieltz, D.M.; Chou, C.W.; Luo, C.W.; Thomas, R.M.; Williams, P. Rapid Commun. Mass Spectrom. 1992, 6, 631.
17. Caprioli, R.M.; Farmer, T.B.; Gile, J. Anal. Chem. 1997, 69, 4751.
18. Skaife, J.J.; Abbott, N.L. Chem. Mater. 1999, 11, 612.
19. de Gennes, P.G. The Physics of Liquid Crystals; Clarendon: Oxford, 1974.
20. Jerome, B. Rep. Prog. Phys. 1991, 54, 391.
21. Janning, J.L. Appl. Phys. Lett. 1972, 21, 173.
22. Flanders, D.C.; Shaver, D.C.; Smith, H.I. Appl. Phys. Lett. 1978, 32, 597.
23. x (ref 21).
24. Ong, H.L.; Hurd, A.J.; Meyer, R.B. J. Appl. Phys. 1985, 57, 186.
25. Ong, H.L. Mol. Cryst. Liq. Cryst. 1985, 144, 17.
26. Wolff, U.; Greubel, W.; Kruger, H. Mol. Cryst. Liq. Cryst. 1973, 23, 187.
27. Kim, S.-R.; Shah, R.R.; Abbott, N.L. Anal. Chem., 2990, 72, 4646.
28. Drawhorn, R.A.; Abbott, N.L. J. Phys. Chem. 1995, 99, 16511.
29. Gupta, V.K.; Abbott, N.L. Phys. Rev. E 1996, 54, R4540.
30. Gupta, V.K.; Abbott, N.L. Science 1997, 276, 1533.
31. Miller, W.J.; Abbott, N.L.; Paul, J.D.; Prentiss, M. Appl. Phys. Lett. 1996, 69, 1852.
32. Gupta, V.K.; Miller, W.J.; Pike, C.L.; Abbott, N.L. Chem. Mater. 1996, 8, 1366.
33. Berreman, D.W. Phys. Rev. Lett. 1972, 28, 1683.
34. Gupta, V.K.; Abbott, N.L. Langmuir 1996, 12, 2587.
35. Shah, R.; Abbott, N.L. J. Am. Chem. Soc. 1999, 121, 11300.
36. Nuzzo, R.G.; Dubois, L.H.; Allara, D.L. J. Am. Chem. Soc. 1990, 112, 558.
37. Skaife, J.J.; Brake, J.M.; Abbott, N.L. Langmuir, in press.
38. Sprinke, J., et al. J. Chem. Phys. 1993, 99, 7012.
39. 4 molecules per square micrometer) from solution, we conclude that nonspecific adsorption from solutions containing 10 nM or less IgG can potentially deplete the IgG in solution to levels that would influence the extent of binding of IgG to the surface of SAMs used in our experiments. For this reason, we used Triton X-100 to minimize the nonspecific adsorption of IgG to the surface of the vial as well as to the SAMs.
40. Maximum extinction of the light transmitted through a cell containing uniformly oriented liquid crystal occurs when One of the crossed polars is oriented parallel to the orientation of the liquid crystal.
41. We chose the average brightness as a measure of uniformity in the optical textures because it is simple to calculate. Other measures of the appearance of the liquid crystal will likely serve as useful indices of the amount of bound IgG.
42. Interference colors result from the transmission of particular wavelengths of light when using a white light source of illumination. The extent of transmission of a particular wavelength of light depends on the retardation, Δnd, where Δn is the birefringence and d is the thickness of the birefringent film. Light propagating through the liquid crystal will be extinguished under conditions where Δnd =jξ,j = O, 1, 2,..., where ξ is the wavelength of light. Interference colors are divided into orders according to the magnitude of the retardation: 0-550 nm (first order), 550-1100 nm (second order), and 1100-1650 nm (third order).
43. Sheller, N.B.; Petrash, S.; Foster, M.D. Langmuir 1998, 14, 4535.