Amino(hydroxymethyl)cyclopentanetriols, an emerging class of potent glycosidase inhibitors - Part II: Synthesis, evaluation, and optimization of β-D-galactopyranoside analogues

ChemBioChem

Volumn 2, Issue 5, 2001, Pages 368-370

  Greul, Jörg N ^a   Kleban, Martin ^a   Schneider, Birgit ^a   Picasso, Sylviane ^b   Jäger, Volker ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Carbohydrate mimics; Cycloaddition; Glycosidases; Hydrolases; Inhibitors

Indexed keywords

AMINOSUGAR; CYCLOPENTANE 1,2,3 TRIOL; CYCLOPENTANE DERIVATIVE; CYCLOPENTANE-1,2,3-TRIOL; ENZYME INHIBITOR; GALACTOSE; GLYCOSIDASE; GLYCOSIDE;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; IC 50; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO SUGARS; CYCLOPENTANES; ENZYME INHIBITORS; GALACTOSE; GLYCOSIDE HYDROLASES; GLYCOSIDES; INHIBITORY CONCENTRATION 50; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035805652     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/1439-7633(20010504)2:5<368::AID-CBIC368>3.0.CO;2-A     Document Type: Article

References (6)

1. a) M. Kleban, P. Hilgers, J. Greul, R. D. Kugler J. Li, S. Picasso, P. Vogel, V. Jäger, ChemBioChem 2001, 2, 365-368;
2. b) V. Jäger, S. Picasso, The 16th ICHC (Montana State University, Bozeman), 1997, Abstr. IL-VI-2.
3. a) M. Kleban, Dissertation, Universität Stuttgart, 1996;
4. b) J. Greul, Dissertation, Universität Stuttgart, 2000;
5. c) J. Greul, Diplomarbeit, Universität Stuttgart, 1996;
6. d) B. Schneider, Diplomarbeit, Universität Stuttgart, 1996.