Inhibition studies of porphobilinogen synthase from Escherichia coli differentiating between the two recognition sites

ChemBioChem

Volumn 2, Issue 5, 2001, Pages 343-354

  Stauffer, Frédéric ^b   Zizzari, Eleonora ^a   Engeloch Jarret, Caroline ^c   Faurite, Jean Philippe ^a   Bobálová, Janette ^d   Neier, Reinhard ^a  

^a Université de Neuchâtel   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Biosynthesis; Inhibitors; Intermediates; Lyases; Porphobilinogen synthase

Indexed keywords

AMINOLEVULINIC ACID; ENZYME INHIBITOR; PORPHOBILINOGEN; PORPHOBILINOGEN SYNTHASE;

ARTICLE; BINDING SITE; DRUG ANTAGONISM; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; KINETICS; METABOLISM;

AMINOLEVULINIC ACID; BINDING SITES; ENZYME INHIBITORS; ESCHERICHIA COLI; KINETICS; PORPHOBILINOGEN; PORPHOBILINOGEN SYNTHASE; SUBSTRATE SPECIFICITY;

EID: 0035805649     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/1439-7633(20010504)2:5<343::AID-CBIC343>3.0.CO;2-1     Document Type: Article

References (2)

1. A.R. Battersby, C.J.R. Fookes, G.W.J. Matcham, E. McDonald, Nature 1980, 285, 17-21.
2. B.Kräutler, Chimia 1987, 41, 277-292.