DNA polymerase β is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

EMBO Journal

Volumn 20, Issue 23, 2001, Pages 6919-6926

  Allinson, S L ^a   Dianova, I I ^a   Dianov, G L ^a  

^a MRC Radiation/Genome Stability Unit   (United Kingdom)

Author keywords

Base excision repair; Cell extracts; DNA polymerase ; NTH1; OGG1

Indexed keywords

5' DEOXYRIBOSEPHOSPHATE LYASE; 8 HYDROXYGUANINE; CELL EXTRACT; DEOXYRIBONUCLEASE; DIHYDROURACIL; DNA; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; LYASE; NUCLEOTIDE; PROTEIN NTH1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; EXCISION REPAIR; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CARBON-OXYGEN LYASES; CELL LINE; DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED); DNA; DNA DAMAGE; DNA POLYMERASE BETA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; FIBROBLASTS; GUANINE; HUMANS; LYASES; MICE; MICE, KNOCKOUT; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; OXYGEN; RECOMBINANT PROTEINS; TIME FACTORS; URACIL;

EID: 0035803497     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.23.6919     Document Type: Article

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