Unprecedented sugar-dependent in vivo antitumor activity of carbohydrate-pendant cis-diamminedichloroplatinum(II) complexes

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 23, 2001, Pages 3045-3047

  Mikata, Yuji ^a   Shinohara, Yoshie ^a   Yoneda, Kazumi ^a   Nakamura, Yuka ^a   Brudziska, Izabela ^a   Tanase, Tomoaki ^a   Kitayama, Takashi ^b   Takagi, Rie ^b   Okamoto, Tadashi ^b   Kinoshita, Isamu ^c   Doe, Matsumi ^c   Orvig, Chris ^d   Yano, Shigenobu ^a  

^a NARA WOMEN'S UNIVERSITY   (Japan)

^b KINKI UNIVERSITY   (Japan)

^c Osaka Prefecture University   (Japan)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIAMINOPROPANE; 1,3 PROPANEDIAMINE; ALKANE DERIVATIVE; CHELATE; CISPLATIN DERIVATIVE; GALACTOSE; GLUCOSE; GLYCOSIDE; LEVO GLUCOSE; MANNOSE; PLATINUM COMPLEX; UNCLASSIFIED DRUG; XYLOSE;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONFORMATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LD 50; MOUSE; SURVIVAL TIME;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOHYDRATE METABOLISM; CARBOHYDRATES; CISPLATIN; DRUG SCREENING ASSAYS, ANTITUMOR; LETHAL DOSE 50; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; ORGANOPLATINUM COMPOUNDS;

EID: 0035803037     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00623-0     Document Type: Article

References (17)