X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 Å resolution

Journal of Molecular Biology

Volumn 311, Issue 1, 2001, Pages 87-100

  Li De La Sierra, I ^a   Munier Lehmann, H ^a   Gilles, A M ^a   Barzu O ^a   Delarue, M ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

AZTMP; Crystal structure; Mycobacterium tuberculosis; Rational drug design; Thymidylate kinase

Indexed keywords

ADENOSINE TRIPHOSPHATE; ENZYME INHIBITOR; MAGNESIUM ION; PHOSPHATE; PHOSPHOTRANSFERASE; THYMIDYLATE KINASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; DRUG DESIGN; ELECTRIC FIELD; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; X RAY ANALYSIS;

EID: 0035800652     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4843     Document Type: Article

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