Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the β-blocker cholesterol-lowering asymptomatic plaque study (BCAPS)

Circulation

Volumn 103, Issue 13, 2001, Pages 1721-1726

  Hedblad, B ^a,b,c   Wikstrand, J ^a,b,c,d   Janzon, L ^a,b,c   Wedel, H ^a,b,c   Berglund, G ^a,b,c,e  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c NORDIC SCHOOL OF PUBLIC HEALTH   (Sweden)

^d ASTRAZENECA R AND D   (Sweden)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Carotid arteries; Drugs; Trials; Ultrasonics

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; FLUINDOSTATIN; LIVER ENZYME; METOPROLOL;

ADULT; ADVERSE DRUG REACTION; AGED; ARTERY MEDIA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CANCER; CARDIOVASCULAR DISEASE; CAROTID ARTERY DISEASE; CLINICAL TRIAL; COMMON CAROTID ARTERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENZYME BLOOD LEVEL; FEMALE; FOLLOW UP; HUMAN; INTIMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0035799330     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.13.1721     Document Type: Article

References (22)

1. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
2. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
3. Effect of lovastatin on early carotid atherosclerosis and cardiovascular events: Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group
4. Pravastatin, Lipids and Atherosclerosis in the Carotid Arteries (PLAC-II)
5. Koupio Atherosclerosis Prevention Study (KAPS): A population-based primary preventive trial of the effect of LDL lowering on atherosclerotic progression in carotid and femoral arteries
6. Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic Mediterranean population: The Carotid Atherosclerosis Italian Ultrasound Study
7. The pathogenesis of atherosclerosis: A perspective for the 1990s
8. Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction
9. Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: The Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
10. Metoprolol versus thiazide diuretics in hypertension: Morbidity results from the MAPHY study
11. The effect of metoprolol on diet-induced atherosclerosis in rabbits
12. The effects of beta-adrenergic blocking agents on atherosclerosis and its complications
13. Role of sympathoadrenal medullary activation in the initiation and progression of atherosclerosis
14. The Maimö Diet and Cancer Study: Design and feasibility
15. A new automated computerised analysing system simplifies readings and reduces the variability in ultrasound measurement of intima-media thickness
16. Inhibition of platelet accumulation by beta1-adrenoreceptor blockade in the thoracic aorta of rabbits to experimental sympathetic activation
17. The role of sympathetic activity in atherogenesis: Effects of β-blockade
18. Prostacyclin synthesis in relation to sympathoadrenal activation
19. Carotid bifurcation atherosclerosis: Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress
20. Pulsatile flow and atherosclerosis in human carotid bifurcation
21. Relation of atherosclerosis to arterial wall shear in the left anterior descending coronary artery of man