Total syntheses of 1-methyl-1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines involving free radical cyclizations induced by tributyltin(IV) hydride

Tetrahedron

Volumn 57, Issue 10, 2001, Pages 1973-1979

  Martínez, Elena ^a   Estévez, Juan C ^a   Estévez, Ramón J ^a   Castedo, Luis ^a  

^a INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

Author keywords

Alkaloids; Biaryls; Chromanones; Cyclization; Isoquinolines; Radical reaction

Indexed keywords

1 (2 BROMOBENZYL)ISOCHROMAN 3 ONE DERIVATIVE; 1 METHYL 1,2,3,4 TETRAHYDRONAPHTHO[2,1 F]ISOQUINOLINE DERIVATIVE; 11,12 DIMETHOXY 1 METHYL 1,2,3,4 TETRAHYDRONAPHTHO[2,1 F]ISOQUINOLINE; 2 (1 PHENANATHRYL)ACETAMIDE DERIVATIVE; 4,5,6A,7 TETRAHYDRODIBENZOCHROMAN 3 ONE DERIVATIVE; 8,9,11,12 TETRAMETHOXY 1 METHYL 1,2,3,4 TETRAHYDRONAPHTHO[2,1 F]ISOQUINOLINE; ACETANILIDE DERIVATIVE; CHROMAN DERIVATIVE; FREE RADICAL; ISOQUINOLINE DERIVATIVE; N [2 [2 (2 BROMOPHENYL) 1 METHOXYETHYL]PHENYLETHYL]ACETAMIDE DERIVATIVE; TRIBUTYLTIN; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0035799147     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)00040-0     Document Type: Article

References (17)

1. Structural aspects of antineoplastic agents - A new approach