Initial isolation and analysis of the human Kv1.7 (KCNA7) gene, a member of the voltage-gated potassium channel gene family

Gene

Volumn 268, Issue 1-2, 2001, Pages 115-122

  Kashuba, Vladimir I ^a,b,c   Kvasha, Sergei M ^a,c   Protopopov, Alexei I ^a,b   Gizatullin, Rinat Z ^a   Rynditch, Alla V ^c   Wahlestedt, Claes ^a   Wasserman, Wyeth W ^a   Zabarovsky, Eugene R ^a,b,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^d ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Gene mapping; Gene structure; NotI linking clone

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; MESSENGER RNA; POTASSIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED CHANNEL FORMING PROTEIN; VOLTAGE GATED POTASSIUM CHANNEL PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE; CHANNEL GATING; CHROMOSOME BAND; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ISOLATION; GENE MAPPING; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; REPOLARIZATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 19; CLONING, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; KIDNEY; LIVER; MICE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS;

EID: 0035795588     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00423-1     Document Type: Article

References (22)

1. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
2. Ausubel F.M., Brent R., Kingston R.E., Moore D.D., Sedman J.G., Smith J.A., Struhl K. Current Topics in Molecular Biology. 1990;Wiley, New York.
3. Bird A.P. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3:1987;342-347.
4. Browne D.L., Gancher S.T., Nutt J.G., Brunt E.R., Smith E.A., Kramer P., Litt M. Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1. Nat. Genet. 8:1994;136-140.
5. Chandy K.G., Gutman G.A. Ligand and Voltage-Gated Ion Channels. Handbook of Receptors and Channels. 1995;1-72 CRC Press, Boca Raton, FL.
6. + channels: generating excitement in pancreatic beta-cells. Diabetes. 45:1996;845-853.
7. Elbein S.C., Hoffman M., Ridinger D., Otterud B., Leppert M. Description of a second microsatellite marker and linkage analysis of the muscle glycogen synthase locus in familial NIDDM. Diabetes. 43:1994;1061-1065.
8. Gish W., States D.J. Identification of protein coding regions by database similarity search. Nat. Genet. 3:1993;266-272.
9. Kalman K., Nguyen A., Tseng-Crank J., Dukes I.D., Chandy G., Hustad C.M., Copeland N.G., Jenkins N.A., Mohrenweiser H., Brandriff B., Cahalan M., Gutman G.A., Chandy K.G. Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7. J. Biol. Chem. 273:1998;5851-5857.
10. Kashuba V.I., Gizatullin R.Z., Protopopov A.I., Li J., Vorobieva N.V., Fedorova L., Zabarovska V.I., Muravenko O.V., Kost-Alimova M., Domninsky D.A., Kiss C., Allikmets R., Zakharyev V.M., Braga E.A., Sumegi J., Lerman M., Wahlestedt C., Zelenin A.V., Sheer D., Winberg G., Grafodatsky A., Kisselev L.L., Klein G., Zabarovsky E.R. Analysis of NotI linking clones isolated from human chromosome 3 specific libraries. Gene. 239:1999;259-271.
11. Makalowski W., Boguski M.S. Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequences. Natl. Acad. Sci. USA. 95:1998;9407-9412.
12. Mein C.A., Esposito L., Dunn M.G., Johnson G.C., Timms A.E., Goy J.V., Smith A.N., Sebag-Montefiore L., Merriman M.E., Wilson A.J., Pritchard L.E., Cucca F., Barnett A.H., Bain S.C., Todd J.A. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat. Genet. 19:1998;297-300.
13. Mott R. EST_GENOME: a program to align spliced DNA sequences to unspliced genomic DNA. Comp. Appl. Biosci. 13:1997;477-478.
14. Protopopov A.I., Gizatullin R.Z., Vorobieva N.V., Protopopova M.V., Kiss C., Kashuba V.I., Klein G., Kisselev L.L., Grafodatsky A.S., Zabarovsky E.R. High resolution FISH mapping of 50 NotI linking clones homologous to genes and cDNAs on human chromosome 3. Chromosome Res. 4:1996;443-447.
15. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Scherf M., Klingenhoff A., Werner T. Highly specific localization of promoter regions in large genomic sequences by PromoterInspector: a novel context analysis approach. J. Mol. Biol. 297:2000;599-606.
17. Shier C.-C., Coghlan M., Sullivan J.P., Gopalakrishnan M. Potassium channels: molecular defects, diseases, and therapeutic opportunities. Pharmacol. Rev. 52:2000;557-593.
18. Songyang Z., Fanning A.S., Fu C., Xu J., Marfatia S.M., Chishti A.H., Crompton A., Chan A.C., Anderson J.M., Cantley L.C. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science. 275:1994;73-77.
19. Wasserman W.W., Fickett J.W. Identification of regulatory regions which confer muscle-specific gene expression. J. Mol. Biol. 278:1998;167-181.
20. Wasserman W.W., Palumbo M., Thompson W., Fickett J.W., Lawrence C.E. Human-mouse genome comparisons to locate regulatory sites. Nat. Genet. 26:2000;225-228.
21. Zabarovsky E.R., Allikmets R., Kholodnyuk I., Zabarovska V.I., Paulsson N., Bannikov V.M., Kashuba V.I., Dean M., Kisselev L.L., Klein G. Construction of representative NotI linking libraries specific for the total human genome and for human chromosome 3. Genomics. 20:1994;312-316.
22. Zabarovsky E.R., Gizatullin R., Podowski R.M., Zabarovska V.I., Xie L., Muravenko O.V., Kozyrev S., Petrenko L., Skobeleva N., Li J., Protopopov A., Kashuba V., Ernberg I., Winberg G., Wahlestedt C. NotI clones in the analysis of the human genome. Nucleic Acids Res. 28:2000;1635-1639.