Decreased expression of c-myc family genes in thymuses from myasthenia gravis patients

Journal of Neuroimmunology

Volumn 115, Issue 1-2, 2001, Pages 199-202

  Nagata, T ^a   Onodera, H ^a   Ohuchi, M ^b   Suzuki, Y ^a   Tago, H ^a   Fujihara, K ^a   Ishii, N ^a   Sugamura, K ^a   Shoji, Y ^a   Handa, M ^a   Tabayashi, K ^a   Itoyama, Y ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SENDAI CITY MEDICAL CENTER   (Japan)

Author keywords

Apoptosis; c myc; Myasthenia gravis; NFkappaB; STAM; Thymus

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; M PROTEIN; MYC PROTEIN; PROTEIN BCL X; PROTHYMOSIN ALPHA;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; MYASTHENIA GRAVIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; APOPTOSIS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASES; DNA-BINDING PROTEINS; FEMALE; HUMANS; MALE; MYASTHENIA GRAVIS; NF-KAPPA B; PHOSPHOPROTEINS; PROTEIN PRECURSORS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS C-REL; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMOSIN; THYMUS GLAND; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS;

EID: 0035795041     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(01)00252-1     Document Type: Article

References (12)

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7. Thymocyte Fas expression is dysregulated in myasthenia gravis patients with anti-acetylcholine receptor antibody
8. Up-regulation of Bcl-2 protein in the myasthenic thymus
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10. Failure to down-regulate Bcl-2 protein in thymic germinal center B cells in myasthenia gravis
11. STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
12. A NF-kappa B/c-myc-dependent survival pathway is targeted by corticosteroids in immature thymocytes