Nitric oxide attenuates signal transduction: Possible role in dissociating caveolin-1 scaffold

Circulation Research

Volumn 88, Issue 2, 2001, Pages 229-236

  Li, Hong ^a   Brodsky, Sergey ^a   Basco, Mary ^a   Romanov, Victor ^a   De Angelis, Dino A ^b   Goligorsky, Michael S ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Caveolae; Cytosolic calcium concentration; Green fluorescent protein; Nitric oxide

Indexed keywords

8 BROMO CYCLIC GMP; CALCIUM ION; CALMODULIN; CAVEOLIN 1; CHOLERA TOXIN B SUBUNIT; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; RECEPTOR; SERPENTINE;

ARTICLE; CELL LABELING; CONTROLLED STUDY; DISSOCIATION; ENZYME REGULATION; FLUORESCENCE; HUMAN; HUMAN CELL; OLIGOMERIZATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

EID: 0035793342     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.88.2.229     Document Type: Article

References (46)

1. Caveolae and caveolins
2. Src tyrosine kinases, G subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin
3. Interaction of a receptor tyrosine kinase, EGF-R, with caveolins: Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities
4. Signal transduction of a G protein-coupled receptor in caveolae: Colocalization of endothelin and its receptor with caveolin
5. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric oxide synthase may explain the "arginine paradox."
6. Signal transduction molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
7. i in caveolae in DDT1 MF-2 smooth muscle cells
8. Caveolin, a protein component of caveolae membrane coats
9. Oligomeric structure of caveolin: Implications for caveolae membrane organization
10. VIP21-caveolin, a membrane protein constituent of the caveolar coat oligomerizes in vivo and in vitro
11. Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: Implications for nitric oxide signaling
12. The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: A green fluorescent protein study
13. Endothelial nitric oxide synthase targeting to caveolae: Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
14. Direct interaction of endothelial nitric oxide synthase and caveolin-1 inhibits synthase activity
15. Dynamic regulation of endothelial nitric oxide synthase: Complementary roles of dual acylation and caveolin interactions
16. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1
17. Reciprocal regulation of endothelial nitric oxide synthase by Ca-calmodulin and caveolin
18. The endothelial nitric-oxide synthase-caveolin regulatory cycle
19. Nitric oxide synthases: Which, where, how, and why?
20. Modulation of bradykinin receptor ligand binding affinity and its coupled G-proteins by nitric oxide
21. Termination of endothelin signaling: Role of nitric oxide
22. Direct demonstration of the IGF-1-induced nitric oxide production by endothelial cells
23. Multiple domains in caveolin-1 control its intracellular traffic
24. Caveolae require intact VAMP for targeted transport in vascular endothelium
25. Human von Willebrand factor (vWF): Isolation of complementary DNA(cDNA) clones and chromosomal location
26. Visualization of caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras
27. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
28. Podokinesis in endothelial cell migration: Role of NO
29. PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides
30. Caveolin-1 and -2 in the pathway of MCDK cells
31. Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules
32. Filipin-dependent inhibition of cholera toxin: Evidence for toxin internalization and activation through caveolae-like domains
33. Separation of caveolae from associated microdomains of GPI-anchored proteins
34. Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia
35. Characterization of bovine endothelial nitric oxide synthase expressed in E. coli
36. Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure
37. Oxygen radicals and signaling
38. Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatase
39. Dynamin-mediated internalization of caveolae
40. Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium
41. Regulated internalization of caveolae
42. Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps
43. VIP 21, a 21-kD membrane protein, is an integral component of trans-Golgi-network-derived transport vesicles
44. Nitric oxide synthase is localized predominantly in the Golgi apparatus and cytoplasmic vesicles of vascular endothelial cells
45. The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide
46. Nitric oxide synthases: Which, where, how and why