Once daily treatment with terbinafine 1% cream (Lamisil®) for one week is effective in the treatment of tinea corporis and cruris. A placebo-controlled study

Mycoses

Volumn 44, Issue 7-8, 2001, Pages 300-306

  Budimulja, Unandar ^a   Bramono, K ^a   Urip, K S ^a   Basuki, S ^b   Widodo, G ^b   Rapatz, G ^c   Paul, C ^c  

^a UNIVERSITY OF INDONESIA   (Indonesia)

^b Tarakan Hospital   (Indonesia)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antimycotic chemotherapy; Lamisil , topical medication; Placebo controlled study; Terbinafine 1 cream; Tinea corporis; Tinea cruris

Indexed keywords

PLACEBO; TERBINAFINE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MICROSCOPY; PATIENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; TINEA CORPORIS; TINEA CRURIS; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADULT; AGED; ANTIFUNGAL AGENTS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; NAPHTHALENES; RANDOMIZED CONTROLLED TRIALS; TINEA; TINEA PEDIS; TREATMENT OUTCOME;

ARTHRODERMATACEAE; TINEA;

EID: 0035788245     PISSN: 09337407     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0507.2001.00672.x     Document Type: Article

References (17)

1. Clayton, Y. M. (1989) In vitro activity of terbinafine. Clin. Exp. Dermatol. 14, 101-103.
2. Petranyi, G., Meingassner, J. G. & Meith, H. (1987) Antifungal activity of the allylamine derivative terbinafine in vitro. Antimicrob. Agents Chemother. 31, 1365-1368.
3. Clayton, Y. M. (1994) Relevance of broad-spectrum and fungicidal activity of antifungals in the treatment of dermatomycoses. Br. J. Dermatol. 130 (Suppl. 43), 7-8.
4. Ryder, N. S. (1989) The mechanism of action of terbinafine. Clin. Exp. Dermatol. 14, 98-100.
5. Ryder, N. S. & Favre, B. (1997) Antifungal activity and mechanism of action of terbinafine. Rev. Contemp. Pharmacother. 8, 275-287.
6. Villars, V. & Jones, T. C. (1989) Clinical efficacy and tolerability of terbinafine (Lamisil) - a new topical and systemic fungal drug for treatment of dermatomycoses. Clin. Exp. Dermatol. 14, 124-127.
7. Berman, B., Ellis, C., Leydon, J., et al. (1992) Efficacy of a 1-week, twice daily regimen of terbinafine 1% cream in the treatment of interdigital tinea pedis: results of placebo-controlled, double-blind, multicentre trials. J. Am. Acad. Dermatol. 26, 956-960.
8. Patel, A., Brookman, S. D., Bullen, M. U., et al. (1999) Topical treatment of interdigital tinea pedis with terbinafine compared to clotrimazole. Aust. J. Dermatol. 40, 197-200.
9. Jones, T. C. (1990) Treatment of dermatomycoses with topically applied allylamines: naftifine and terbinafine. J. Dermatol. Treat. 1 (Suppl. 2), 29-32.
10. Evans, E. G. V., Shah, J. M. & Joshipura, R. C. (1992) One-week treatment of tinea corporis and tinea cruris with terbinafine (Lamisil) 1% cream: a placebo controlled study. J. Dermatol. Treat. 3, 181-184.
11. Zaias, N., Berman, B., Cordero, C. N., et al. (1993) Efficacy of a 1-week, once-daily regimen of terbinafine 1% cream in the treatment of tinea cruris and tinea corporis. J. Am. Acad. Dermatol. 29, 646-648.
12. Casagrande, J. T., Pike, M. C. & Smith, P. G. (1978) An improved approximate formula for calculating sample sizes for comparing two binomial distributions. Biometrics 34, 484-486.
13. Finlay, A. Y. (1999) Skin and nail fungi almost beaten. Br. Med. J. 319, 71-72.
14. Meinhof, W., Girardi, R. M. & Stracke, A. (1984) Patient noncompliance in dermatomycosis: results of a survey among dermatologists, general practitioners and patients. Dermatologica. 169 (Suppl. 1), 57-66.
15. Faergemann, J., Zehender, H. & Boukhabza, A. (1995) Comparison of terbinafine levels in stratum corneum and dermis-epidermis (without stratum corneum) after topical or topical combined with oral therapy in healthy volunteers. J. Eur. Acad. Dermatol. Venereol. 5 (Suppl. 1), 94.
16. Hill, S., Thomas, R., Smith, S. G. & Finlay, A. Y. (1990) Stratum corneum kinetics of topical terbinafine: fungicidal concentrations with short course therapy. Br. J. Dermatol. 125, 482.
17. Evans, E. G. (1997) Tinea pedis: clinical experience and efficacy of short treatment. Dermatology 194 (Suppl. 1), 3-6.