Clinical effects of brown seaweed, Undaria pinnatifida (wakame), on blood pressure in hypertensive subjects

Journal of Clinical Biochemistry and Nutrition

Volumn 30, Issue , 2001, Pages 43-53

  Hata, Yoshiya ^a,b   Nakajima, Kumiko ^a   Uchida, Jun ichi ^a   Hidaka, Hidemasa ^c   Nakano, Takahisa ^d  

^a KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Vascular Science Laboratory   (Japan)

^c TOKIWA UNIVERSITY   (Japan)

^d RIKEN VITAMIN CO LTD   (Japan)

Author keywords

Dietary treatment; Hypertension; Seaweed; Wakame

Indexed keywords

ADULT; AGED; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; CLINICAL TRIAL; DIASTOLIC BLOOD PRESSURE; DIET SUPPLEMENTATION; FEMALE; HUMAN; HYPERTENSION; MALE; SEAWEED; SYSTOLIC BLOOD PRESSURE; UNDARIA PINNATIFIDA;

ALGAE; UNDARIA PINNATIFIDA;

EID: 0035788194     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.30.43     Document Type: Article

References (38)

1. Yamori, Y., Nara, Y., Tsubouchi, T., Sogawa, Y., Ikeda, K., and Horie, R. (1986): Dietary prevention of stroke and its mechanisms in Stroke-Prone spontaneously hypertension rats-preventive effect of dietary fibre and palmitoleic acid. J. Hypertens., 4, Suppl. 3, S449-S452.
2. Krotkiewski, M., Aurell, M., Holm, G., Grimby, G., and Szczepanik, J. (1991): Effects of a sodium-potassium ion-exchanging seaweed preparation in mild hypertension. Am. J. Hypertens., 4, 483-488.
3. Tsuji, K., Oshima, S., Matsuzaki, E., Nakamura, A., Innami, S., Tezuka, T., and Suzuki, S. (1968): Effect of polysaccharides on cholesterol metabolism (Part 1). Eiyogaku Zasshi, 26, 113-122.
4. Torsdottir, I., Alpsten, M., Holm, G., Sandberg, A., and Tolli, J. (1991): A small dose of soluble alginate-fiber affects postprandial glycemia and gastric emptying in humans with diabetes. J. Nutr., 121, 795-799.
5. Hata, Y., Yamamoto, M., Ohni, M., Nakajima, K., Nakamura, Y., and Takano, T. (1996): A placebo controlled study of the effect of sour milk on blood pressure in hypertensive subjects. Am. J. Clin. Nutr., 64, 767-771.
6. Steiner, M., Khan, A.H., Holbert, D., and Lin, R.I. (1996): A double-blind cross over study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids. Am. J. Clin. Nutr., 64, 866-870.
7. Nakajima, K., Hata, Y., Osono, Y., Hamura, M., Kobayashi, S., and Watanuki, M. (1995): Antihypertensive effect of extracts of Lactobacillus casei in patients with hypertension. J. Clin. Biochem. Nutr., 8, 181-187.
8. Sharpe, S.J., Gamble, G.D., and Shrpe, D.N. (1994): Cholesterol-lowering and blood pressure effects of immune milk. Am. J. Clin. Nutr., 59, 929-934.
9. Morris, M.C., Taylor, J.O., Stampfer, M.J., Rosner, B., and Sacks, F.M. (1993): The effect of fish oil on blood pressure in mild hypertensive subjects: A randomized crossover trial. Am. J. Clin. Nutr., 57, 59-64.
10. Moran, J.P., Cohen, L., and Greene, J.M. (1993): Plasma ascorbic acid concentrations relate inversely to blood pressure in human subjects. Am. J. Clin. Nutr., 57, 213-217.
11. Japan Atherosclerosis Society (1997): Investigation Committee of Guideline for Diagnosis and Treatment of Hyperlipidemia in adults. J. Jpn. Atherosclerosis Soc., 25, 1-34.
12. Japan Hypertension Society Working Group (Kaneko, Y. et al., 1994): Guideline for clinical evaluation of drugs in research and development, in Handbook of Guidelines for Development of New Drugs, Yakugyo Jiho, Tokyo, pp. 222-239.
13. Witteman, J.C.M., Grobbee, D.E., Derkx, F.H.M., Bouillon, R., Brujin, A.M., and Hofman, A. (1994): Reduction of blood pressure with oral magnesium supplementation in women with mild to moderate hypertension. Am. J. Clin. Nutr., 60, 129-135.
14. Lahate, M. (1991): Marine algae as sources of fibre: determination of soluble and insoluble dietary fiber contents in some "sea vegetable." J. Sci. Food Agric., 54, 587-594.
15. Sakurai, Y. (1994): Alginic acid, in General Food Dictionary, 6th ed., Dobun Shoin, Tokyo, p. 39.
16. Humphrey, E.R., and Triffitt, J.T. (1968): Absorption by the rat of alginate labeled with carbon-14. Nature, 219, 1172-1173.
17. Mitchell, W.D., and Eastwood, M.A. (1978): Dietary fiber and colon function, in Fiber in Human Nutrition, ed. by Spiller, G.A., and Amen, R.J., Plenum Press, New York, pp. 185-206.
18. Mitsuoka, T. (1994): Current status and future prospects of studies on intestinal flora and dietary factors, in Intestinal Flora and Dietary Factors, ed. by Mitsuoka, T., Gakkai Shuppan Center, Tokyo, pp. 1-14.
19. Eastwood, M.A., Eastwood, J., and Wan, M. (1978): Epidemiology of bowel disease, in Fiber in Human Nutrition, ed. by Spiller, G.A., and Amen, R.J., Plenum Press, New York, pp. 207-240.
20. Story, J.A., Kritchevsky, D., and Eastwood, M.A. (1979): Dietary fibre-bile acid interactions, in Dietary Fiber-Chemistry and Nutrition, ed. by Inglett, G.E., and Falkenag, S.I., Academic Press, New York, pp. 49-55.
21. Kloareg, G., Dermarty, M., and Mabean, S. (1987): Ion-exchange properties of isolated cell walls of brown algae. J. Exp. Bot., 38, 1652-1662.
22. Tsuji, K., Tsuji, E., Nakagawa, Y., and Suzuki, S. (1988): Effects of Na-binding capacity of dietary fibers on blood pressure in spontaneously hypertensive rats. J. Home Econom. Jpn., 39, 187-195.
23. Harlan, W.R., and Harlan, L.C. (1995): Blood pressure and calcium and magnecium intake, in Hypertension-Pathophysiology, Diagnosis and Management, 2nd ed., ed. by Laragh, J.H., and Briwn, B.M., Raven Press, New York, pp. 1143-1154.
24. McCarron, D.A., Morris, C.D., and Cole, C. (1982): Dietary calcium in human hypertension, Science, 217, 267-269.
25. McCarron, D.A., and Morris, C.D. (1985): Blood pressure response to oral calcium in persons with mild to moderate hypertension. Ann. Int. Med., 103, 825-831.
26. Oka, Y., Kiriyama, S., and Toshida, A. (1973): Sterol composition of fruits, fungi, marine algae and tea, coffee and cocoa. Jpn. Soc. Food Nutr., 26, 317-327.
27. Ilias, A.M., Connor, W.E., Lin, D.S., and Ahmad, M.U. (1985): Sterol composition of some seaweed. Fett Seifen Anstrichm., 87, 345-346.
28. Hagiwara, H., Wakita, K., Inada, Y., and Hirose, S. (1986): Fucosterol decreases angiotensin converting enzyme levels with reduction of glucocorticoid receptors in endothelial cells. Biochem. Biophys. Res. Commun., 139, 348-352.
29. Hagiwara, H., Shimonaka, M., Morisaki, M., Ikekawa, N., and Inada, Y. (1984): Sitosterol stimulative production of plasminogen activator in cultured endothelial cells from bovine carotid artery. Thromb. Res., 33, 363-370.
30. Shimonaka, M., Hagiwara, H., Kojima, S., and Inada, Y. (1984): Successive study on the production of plasminogen activator in cultured endothelial cells by phytosterol. Thromb. Res., 36, 217-222.
31. Suetsuna, K., and Nakano, T. (2000): Identification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnantifida). J. Nutr. Biochem., 11, 450-454.
32. Nara, Y., Miura, A., Moriguchi, H., Mpriguchi, Y., and Yamori, Y. (1997): Dietary treatment. Jpn. Circ. J., 61, Suppl. 1, 66.
33. Ren, D., Noda, H., Amano, H., Nishino, T., and Nishizawa, K. (1994): Study on antihypertensive and antihyperlipidemic effects of marine algae. Fish. Sci., 60, 83-88.
34. Tani, M., Stoh, M., Tani, Y., and Hayasaki, K. (1995): Influence of cholesterol metabolism on wakame in rats. Nippon Nogei kagaku Kaishi, 69, Suppl., 153(abs).
35. Ames, R.P. (1983): Negative effects of diuretics drugs on metabolic risk factors for coronary heart disease. Am. J. Cardiol., 51, 632-638.
36. Nakamura, H. (1987): Effects of antihypertensive drugs on plasma lipids. Am. J. Cardiol., 60, 24E-28E.
37. Hollenberg, N.K. (1990): Management of hypertension: Considerations involving cardiovascular risk reduction. J. Cardiovasc. Pharmacol., 15, Suppl., S37-S38.
38. Murata, M., Ishihara, K., and Saito, H. (1999): Hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown seaweed, Undaria piannatifida (wakame). J. Nutr., 129, 146-151.