The first three-dimensional structure of phosphofructokinase from Saccharomyces cerevisiae determined by electron microscopy of single particles

Journal of Structural Biology

Volumn 136, Issue 3, 2001, Pages 167-180

  Ruiz, Teresa ^a   Kopperschläger, Gerhard ^b   Radermacher, Michael ^a  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

CTF correction; Electron microscopy; Glycolytic enzyme; Phosphofructokinase; Radon transforms; Saccharomyces cerevisiae; Simultaneous alignment; Three dimensional reconstruction; Vitreous ice

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ICE;

ALPHA CHAIN; ARTICLE; BETA CHAIN; CALCULATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBUNIT; EUKARYOTE; IMAGE RECONSTRUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; SACCHAROMYCES CEREVISIAE; THREE DIMENSIONAL IMAGING;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0035782688     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsbi.2002.4440     Document Type: Article

References (38)

1. Baumeister, W., and Steven, A. C. (2000) Macromolecular electron microscopy in the era of structural genomics. Trends Biochem. Sci. 25, 624-631.
2. Blangy, D. (1968) Phosphofructokinase from E. coli: Evidence for a tetrameric structure of the enzyme. FEBS Lett. 2, 109-111.
3. Carazo, J. M., Wagenknecht, T., and Frank, J. (1989) Variations of the three-dimensional structure of the Escherichia coli ribosome in the range of overlap views. An application of the methods of multicone and local single-cone three-dimensional reconstruction. Biophys. J. 55, 465-477.
4. Evans, P. R. (1992) Activity and allosteric regulation in bacterial phosphofructokinase. Proceedings of the Robert A. Welch Foundation Conference on Chemical Research XXXVI: Regulation of Proteins by Ligands. Houston, Texas, pp. 39-54.
5. Evans, P. R., Farrants, G. W., and Lawrence, M. C. (1986) Crystallographic structure of allosterically inhibited phosphofruc-tokinase at 7 Å resolution. J. Mol. Biol. 191, 713-720.
6. Evans, P. R., and Hudson, P. J. (1979) Structure and control of phosphofructokinase from Bacillus stearothermophilus. Nature 279, 500-504.
7. Goldhammer, A. R., and Paradies, H. H. (1979) Phosphofructokinase: Structure and function. Curr. Top. Cell. Regul. 15, 109-141.
8. Heinisch, J. (1986) Isolation and characterization of the two structural genes coding for phosphofructokinase in yeast. Mol. Gen. Genet. 202, 75-82.
9. Heinrich, R., Rapoport, S. M., and Rapoport, T. A. (1977) Metabolic regulation and mathematical models. Prog. Biophys. Mol. Biol. 32, 1-82.
10. Hofmann, E. (1976) The significance of phosphofructokinase to the regulation of carbohydrate metabolism. Rev. Physiol. Biochem. Pharmacol. 75, 1-68.
11. Hofmann, E., and Kopperschläger, G. (1982) Phosphofructokinase from yeast. Methods Enzymol. 90, 49-60.
12. Kiselev, N. A., Stel'mashchuk, V. J., and Nissler, K. (1979) Quaternary structure of phosphofructokinase according to the data of electron-microscopy. Dokl. Akad. Nauk SSSR 247, 237-239.
13. Kopperschläger, G., Bär, J., Nissler, K., and Hofmann, E. (1977) Physicochemical parameters and subunit composition of yeast phosphofructokinase. Eur. J. Biochem. 81, 317-325.
14. Kopperschläger, G., Bär, J., and Stellwagen, E. (1993) Limited proteolysis of yeast phosphofructokinase. Sequence locations of cleavage sites created by the actions of different proteinases. Eur. J. Biochem. 217, 527-533.
15. Kotlarz, D., and Buc, H. (1982) Phosphofructokinases from Escherichia coli. Methods Enzymol. 90, 60-70.
16. Kriegel, T., Behlke, J., and Kopperschläger, G. (1987) Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase. Biomed. Biochim. Acta 46, 349-355.
17. Lanzavecchia, S., Bellon, P. L., and Radermacher, M. (1999) Fast and accurate three-dimensional reconstruction from projections with random orientations via radon transforms. J. Struct. Biol. 128, 152-164.
18. Laurent, M., Tijane, M. N., Roucous, C., Seydoux, F. J., and Tardieu, A. (1984) Solution X-ray scattering studies of the yeast phosphofructokinase allosteric transition. Characterization of an ATP-induced conformation distinct in quaternary structure from the R and T states of the enzyme. J. Biol. Chem. 259, 3124-3126.
19. Marabini, R., and Carazo, J. M. (1994) Pattern-recognition and classification of images of biological macromolecules using artificial neural networks. Biophys. J. 66, 1804-1814.
20. Marco, S., Chagoyen, M., de la Fraga, L. G., Carazo, J. M., and Carrascosa, J. L. (1996) A variant to the random approximation of the reference-free alignment algorithm. Ultramicroscopy 66, 5-10.
21. Nissler, K., Hofmann, E., Stel'maschchuk, V., Orlova, E., and Kiselev, N. (1985) An electron microscopy study of the quarternary structure of yeast phosphofructokinase. Biomed. Biochim. Acta 44, 251-259.
22. Obmolova, G., Kopperschläger, G., Heinisch, J., and Rypniewski, W. R. (1998) Crystallization and preliminary X-ray analysis of the 12S form of phosphofructokinase from Saccharomyces cerevisiae. Acta Crystallogr. Sect. D: Biol. Crystallogr. 54, 96-98.
23. Plietz, P., Damaschun, G., Kopperschläger, G., and Muller, J. J. (1978) Small-angle x-ray scattering studies on the quaternary structure of phosphofructokinase from baker's yeast. FEBS Lett. 91, 230-232.
24. Radermacher, M. (1988) Three-dimensional reconstruction of single particles from random and nonrandom tilt series. J. Electron Microsc. Tech. 9, 359-394.
25. Radermacher, M. (1997) Radon transform techniques for alignment and 3D reconstruction from random projections. Scanning Microsc. Int. Supple. (in press).
26. Radermacher, M. (2001) Appendix: Simultaneous rotational and translational alignment. J. Struct. Biol. 135, 35-37.
27. Radermacher, M., and Hoppe, W. (1980) Properties of 3-D reconstructions from projections by conical tilting compared to single axis tilting, pp. 132-133. 7th European Congress of Electron Microscopy, Vol. 1, Den Haag.
28. Radermacher, M., Ruiz, T., Wieczorek, H., and Grüber, G. (2001) The structure of the V1-ATPase determined by three-dimensional electron microscopy of single particles. J. Struct. Biol. 135, 26-37.
29. Radermacher, M., Wagenknecht, T., Verschoor, A., and Frank, J. (1987) Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit. J. Microsc. 146, 113-136.
30. Reuter, R., Eschrich, K., Schellenberger, W., and Hofmann, E. (1979) Kinetic modelling of yeast phosphofructokinase. Acta Biol. Med. Germanica 38, 1067-1079.
31. Rypniewski, W. R., and Evans, P. R. (1989) Crystal structure of unliganded phosphofructokinase from Escherichia coli. J. Mol. Biol. 207, 805-821.
32. Saxton, W. O., and Baumeister, W. (1982) The correlation averaging of a regularly arranged bacterial cell envelope protein. J. Microsc. 127, 127-138.
33. Shirakihara, Y., and Evans, P. R. (1988) Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products. J. Mol. Biol. 204, 973-994.
34. Sols, A. (1981) Multimodulation of enzyme activity. Curr. Top. Cell. Regul. 19, 77-101.
35. Stöffler, G., and Stöffler-Meilicke, M. (1983) The ultrastructure of macromolecular complexes studied with antibodies. In Tesche, H. (Ed.), Modern Methods in Protein Chemistry; pp. 409-455, De Gruyter.
36. Tischendorf, G. W., Zeichhardt, H., and Stöffler, G. (1974) Determination of the localization of proteins L14, L17, L18, L19, L22 and L23 on the surface of the 50S ribosomal subunit of Escherichia coli by immuno-electron microscopy. Mol. Gen. Genet. 134, 187-208.
37. Uyeda, K. (1979) Phosphofructokinase. Adv. Enzymol. 48, 193-244.
38. van Heel, M., Keegstra, W., Schutter, W., and van Bruggen, E. J. F. (1982) Arthropod hemocyanin structures studied by image analysis. In Wood, E. J. (Ed.), Life Chemistry Reports, Suppl. 1, The Structure and Function of Invertebrate Respiratory Proteins, EMBO Workshop, pp. 69-73.