Specificity pocket water network and its role in the activity of proteolytic enzymes: Revealed by crystal structures of trypsin

Journal of Biochemistry, Molecular Biology and Biophysics

Volumn 5, Issue 6, 2001, Pages 559-565+VIII

  Johnson, A ^a   Damodharan, L ^a   Pattabhi, Vassantha ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Active site geometry; Activity of trypsin; Autolysate; Network of water molecules; Recognition amino acid water interaction

Indexed keywords

ALPHA TRYPSIN; AMINO ACID; ASPARTIC ACID; BETA TRYPSIN; EPSILON TRYPSIN; HISTIDINE; PROTEINASE; SERINE; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOLYSIS; CHEMICAL INTERACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GEOMETRY; HYDRATION; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN CONFORMATION; PROTEIN ISOLATION; SWINE; WATER STRUCTURE; WATER TRANSPORT;

EID: 0035761657     PISSN: 10258140     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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