Targets of treatment in the acute phase of cerebral infarction

Clinical Neurology

Volumn 41, Issue 12, 2001, Pages 1052-1054

  Tanaka, Kortaro ^a   Fukuuchi, Yasuo ^a   Nogawa, Shigeru ^a   Ito, Daisuke ^a   Suzuki, Shigeaki ^a   Dembo, Tomohisa ^a   Kosakai, Arifumi ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Cerebral infarction; CREB; Free radical; Oligodendrocyte progenitor cells; Treatment

Indexed keywords

3 NITROTYROSINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FREE RADICAL; HYDROXYL RADICAL; NITRIC OXIDE; NORPHENAZONE; SERINE; SUPEROXIDE;

ARTICLE; BLOOD VESSEL WALL; BRAIN INFARCTION; BRAIN INJURY; BRAIN PROTECTION; CELL ACTIVATION; HUMAN; JAPAN; NERVE CELL; NERVE CELL PLASTICITY; OLIGODENDROGLIA; PROTEIN PHOSPHORYLATION; REPERFUSION;

ACUTE-PHASE REACTION; CEREBRAL INFARCTION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FREE RADICAL SCAVENGERS; FREE RADICALS; HUMANS; OLIGODENDROGLIA; PHOSPHORYLATION; STEM CELLS;

EID: 0035761488     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Tanaka K, Shirai T, Nagata E, et al: Immunohistochemical detection of nitrotyrosine in postischemic cerebral cortex in gerbil. Neurosci. Lett. 235: 85-88, 1997
2. Tanaka K: Alteration of second messengers during acute cerebral ischemia-adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP response element binding protein. Prog. Neurobiol 65: 173-207, 2001
3. Tanaka K, Nogawa S, Ito D, et al: Phosphorylation of cyclic AMP response element binding protein (CREB) in oligodendrocytes in the corpus callosum after focal cerebral ischemia in the rat. J. Cereb Blood Flow Metab. 21: 1177-1188, 2001
4. Tanaka K, Nogawa S, Ito D, et al: Activation of NG2-positive oligodendrocyte progenitor cells during postischemic reperfusion in the rat brain. Neuroreport 12: 2169-2174, 2001
5. Kondo T, Raff M: Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 289: 1754-1757, 2000