Photonic Force Microscopy: Simulation of principles and applications

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 4431, Issue , 2001, Pages 75-86

  Rohrbach, Alexander ^a   Florin, Ernst Ludwig ^a   Stelzer, Ernst H K ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

3D position detection; Optical forces; Optical trapping; Particle tracking; Photonic force microscopy; Scattering; Single molecules

Indexed keywords

COHERENT LIGHT; COMPUTER SIMULATION; LIGHT INTERFERENCE; LIGHT SCATTERING; OPTICAL RESOLVING POWER; PHOTONS; SCANNING; THERMAL NOISE;

PHOTONIC FORCE MICROSCOPY;

MICROSCOPIC EXAMINATION;

EID: 0035759621     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.447404     Document Type: Conference Paper

References (19)

1. L.P. Ghislain and W.W. Webb, "Scanning-force microscope based on an optical trap," Optics Letters 18, 1678-80 (1993).
2. E.-L. Florin, A. Pralle, J.K.H. Hörber and E.H.K. Stelzer, "Photonic force microscope (PFM) based on optical tweezers and two-photon excitation for biological applications," Journal of Structural Biology 119, 202-211 (1997).
3. Pralle A, Florin E-L, Stelzer EHK and H. JKH, "Photonic Force Microscopy: A new tool providing a new method to study membranes at the molecular level," Single Molec 1, 129-133 (2000).
4. A. Ashkin, J.M. Dziedzic, J.E. Bjorkholm and S. Chu, "Observation of a single-beam gradient force optical trap for dielectric particles," Opt. Letters 11, 288-290 (1986).
5. E.-L. Florin, A. Pralle, E.H.K. Stelzer and J.K.H. Hörber, "Photonic force microscope calibration by thermal noise analysis," Applied Physics A 66, S75-S78 (1998).
6. L. Ghislain, N. Switz and W. Webb, "Measurement of small forces using an optical trap," Review Of Scientific Instruments 65, N9 (Sep), 2762-2768 (1994).
7. F. Gittes, B. Schnurr, P.D. Olmsted, F.C. MacKintosh and C.F. Schmidt, "Microscopic Viscoelasticity: Shear Moduli of Soft Materials Determined from Thermal Fluctuations," Phys.Rev.Lett. 79, 3286-3289 (1997).
8. A. Pralle, E.-L. Florin, E.H.K. Stelzer and J.K.H. Hörber, "Local viscosity probed by photonic force microscopy," Applied Physics A 66, S71-S73 (1998).
9. A. Pralle, P. Keller, E.-L. Florin, K. Simons and J.K.H.H. Hörber, "Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells," The Journal of Cell Biology 148, 997-1007 (2000).
10. E.-L. Florin, J.K.H. Hörber and E.H.K. Stelzer, "High-resolution axial and lateral position sensing using two-photon excitation of fluorophores by a continuous Nd:YAG laser," Applied Physics Letters 69, 446-448 (1996).
11. M.W. Allersma, F. Gittes, M.J. deCastro, R.J. Stewart and C.F. Schmidt, "Two-dimensional tracking of ncd motility by back focal plane interferometry.," Biophysical Journal 74, 1074-1085 (1998).
12. F. Gittes and C.F. Schmidt, "Interference model for back-focal-plane displacement detection in optical tweezers," Opt. Letters 23, 7-9 (1998).
13. A. Pralle, M. Prummer, E.-L. Florin, E.H.K. Stelzer and J.K.H. Hörber, "Three-dimensional position tracking for optical tweezers by forward scattered light," Microscopy Research and Techniques 44, 378-386 (1999).
14. A. Rohrbach and E.H.K. Stelzer, "Three-dimensional position detection of optically trapped dielectric particles," submitted, (2001).
15. S. Jeney, E.-L. Florin and J.K.H. Hörber, "Use of Photonic Force Microscopy to study single-motor-molecule mechanics," Kinesin Protocols, I. Vernos, (Humana Press, Totowa, NJ, 2000) pp. 91-107.
16. A. Rohrbach and E.H.K. Stelzer, "Optical trapping of dielectric particles in arbitrary fields," J. Opt. Soc. Am. A 18, 839-853 (2001).
17. M. Mansuripur, "Certain computational aspects of vector diffraction problems," J. Opt. Soc. Am. A 6, 786-805 (1989).
18. C. Bohren and D.R. Huffman, "Absorption and scattering of light by small particles," Absorption and scattering of light by small particles, (Wiley Science Paperback, New York, 1998) pp. 95.
19. P. Török, P.D. Higdon and T. Wilson, "On the general properties of polarised light conventional and confocal microscopes," Opt. Comm. 148, 300-315 (1998).