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Pharmacogenomics Journal
Volumn 1, Issue 4, 2001, Pages 288-292
CYP2C9*3 influences the metabolism and the drug-interaction of candesartan in vitro
Author keywords

Candesartan; CYP2C9; In vitro; Inhibition; Metabolism; Polymorphism; Warfarin
Indexed keywords

ANTICOAGULANT AGENT; ANTIHYPERTENSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; CANDESARTAN; CYP2C9 PROTEIN, HUMAN; CYTOCHROME P450; LEUCINE; RECOMBINANT PROTEIN; STEROID 16ALPHA MONOOXYGENASE; STEROID MONOOXYGENASE; TETRAZOLE DERIVATIVE; UNSPECIFIC MONOOXYGENASE; WARFARIN;
EID: 0035753492     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500063     Document Type: Article
Times cited : (27)
References (5)
  • 1
    • 0027431141 scopus 로고
    • Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1 -[[2′-(1 H-ttrazol-5-yl)biphenyl-4-yl]methyl]-1 H-benzimidazole-7-carboxylic acid (CV-11874), and its prodrug, (±)-1 -(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1 -[[2′-(1 H-tetrazol-5-yl)biphenyl-4-yl]methyl]-l H-benzimidazole-7-carboxylate (TCV-116)
    • Shibouta Y, Inada Y, Ojima M, Wada T, Noda M, Sanada T et al. Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1 -[[2′-(1 H-ttrazol-5-yl)biphenyl-4-yl]methyl]-1 H-benzimidazole-7-carboxylic acid (CV-11874), and its prodrug, (±)-1 -(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1 -[[2′-(1 H-tetrazol-5-yl)biphenyl-4-yl]methyl]-l H-benzimidazole-7-carboxylate (TCV-116). J Pharm Exp Ther1993; 266: 114-120.
    • (1993) J Pharm Exp Ther , vol.266 , pp. 114-120
    • Shibouta, Y.1    Inada, Y.2    Ojima, M.3    Wada, T.4    Noda, M.5    Sanada, T.6
  • 2
    • 0031757056 scopus 로고    scopus 로고
    • Candesartan cilexetil
    • McClellan KJ, Coa KL. Candesartan cilexetil. Drugs 1998; 56: 847-869.
    • (1998) Drugs , vol.56 , pp. 847-869
    • McClellan, K.J.1    Coa, K.L.2
  • 3
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P4502C9: An enzyme of major importance in human metabolism
    • Miners JO, Birkett D). Cytochrome P4502C9: an enzyme of major importance in human metabolism. Br J Clin Pharmocol 1998; 45: 525-538.
    • (1998) Br J Clin Pharmocol , vol.45 , pp. 525-538
    • Miners, J.O.1    Birkett, D.2
  • 4
    • 0028861660 scopus 로고
    • Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese
    • Wang SI, Huang I, Lai MD, Tsai JJ. Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese. Pharmacogenetics 1995; 5: 37-42.
    • (1995) Pharmacogenetics , vol.5 , pp. 37-42
    • Wang, S.I.1    Huang, I.2    Lai, M.D.3    Tsai, J.J.4
  • 5
    • 0030868490 scopus 로고    scopus 로고
    • Genetic analysis of CYP2C9 polymorphism in a Japanese population
    • Nasu K, Kubota T, Ishizaki T. Genetic analysis of CYP2C9 polymorphism in a Japanese population. Pharmacogenetics 1997; 7: 405-449.
    • (1997) Pharmacogenetics , vol.7 , pp. 405-449
    • Nasu, K.1    Kubota, T.2    Ishizaki, T.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.