Statistical methods for assessing stability of compounds in whole blood for clinical bioanalysis

Drug Information Journal

Volumn 35, Issue 4, 2001, Pages 1261-1270

  Kringle, Robert ^a   Hoffman, David ^a   Newton, John ^a   Burton, Regina ^a  

^a Sanofi Synthelabo Inc   (United Kingdom)

Author keywords

Equivalence; Fieller's method; Linear regression; Stability

Indexed keywords

ARTICLE; BLOOD; DRUG STABILITY; DRUG STORAGE; LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; ROOM TEMPERATURE; STATISTICAL ANALYSIS;

EID: 0035739764     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: 10.1177/009286150103500423     Document Type: Article

References (5)

1. Bioanalytical method validation - A revisit with a decade of progress
2. A new approach for dealing with the stability of drugs in biological fluids
3. A fundamental formula in the statistics of biological assay, and some applications