Role of chromosomal passenger complex in chromosome segregation and cytokinesis

Cell Structure and Function

Volumn 26, Issue 6, 2001, Pages 653-657

  Terada, Yasuhiko ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

AIM 1; Aurora B; Chromosomal passenger; Chromosome segregation; Cytokinesis; INCENP; Survivin

Indexed keywords

AURORA B KINASE; CHROMOSOME PROTEIN; HISTONE H3; PROTEIN KINASE; SURVIVIN; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; CENTROMERE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOKINESIS; DROSOPHILA; MACROMOLECULE; MAMMAL; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REVIEW; TELOPHASE;

ANIMALS; CELL DIVISION; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; CHROMOSOMES; KINESIN; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES;

ANIMALIA; MAMMALIA;

EID: 0035736346     PISSN: 03867196     EISSN: None     Source Type: Journal    
DOI: 10.1247/csf.26.653     Document Type: Review

References (35)

1. Pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis
2. INCENP binds the aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
3. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation
4. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
5. The conserved protein kinase Ip11 regulates microtubule binding to kinetochores in budding yeast
6. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
7. The Aurora/Ip11p kinase family: Regulators of chromosome segregation and cytokinesis
8. Reversible histone modifications and the chromosome cell cycle
9. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast
10. Signaling to chromatin through histone modifications
11. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
12. Core histone N-termini play an essential role in mitotic chromosome condensation
13. Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans
14. IAP family proteins-suppressors of apoptosis
15. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
16. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis
17. Aurora/Ip11p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
18. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
19. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
20. Mitotic phosphorylation of histone H3 is governed by Ip11/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes
21. Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
22. Down-regulation of an AIM-1 kinase couples with megakaryocytic endomitosis of human hematopoietic cells
23. Heterogeneity and microtubule interaction of the CHO1 antigen, a mitosis-specific kinesin-like protein. Analysis of subdomains expressed in insect sf9 cells
24. A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis
25. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles
26. A nematode kinesin required for cleavage furrow advancement
27. Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4
28. Cleavage furrows formed between centrosomes lacking an intervening spindle and chromosomes contain microtubule bundles, INCENP, and CHO1 but not CENP-E
29. AIR-2: An Aurora/Ip11-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
30. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone
31. Mammalian aurora B/AIM-1 phosphorylates INCENP and targets it to the centromeres during prophase-metaphase
32. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ip11-like midbody-associated protein mitotic kinase in human cancer cells
33. Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation
34. AIM-1: A mammalian midbody-associated protein required for cytokinesis
35. Phosphorylation of histone H3 is required for proper chromosome condensation and segregation