Plasma total transcobalamin I: Ethnic/racial patterns and comparison with lactoferrin

American Journal of Clinical Pathology

Volumn 116, Issue 4, 2001, Pages 576-580

  Carmel, Ralph ^a   Brar, Shabneet ^a   Frouhar, Zohreh ^a  

^a NEW YORK METHODIST HOSPITAL   (United States)

Author keywords

Blacks; Cobalamin; Lactoferrin; Race; Sex; Transcobalamin I; Whites

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; COBALAMIN; CREATININE; HAPTOCORRIN; HOMOCYSTEINE; LACTATE DEHYDROGENASE; LACTOFERRIN; PROTEIN;

ADULT; AGED; ARTICLE; BONE MARROW CELL; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMOGRAPHY; ETHNIC GROUP; HUMAN; INTERMETHOD COMPARISON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RACE DIFFERENCE; RADIOIMMUNOASSAY;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; ASIAN AMERICANS; ASIAN CONTINENTAL ANCESTRY GROUP; CONTINENTAL POPULATION GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HISPANIC AMERICANS; HUMANS; LACTOFERRIN; MALE; MIDDLE AGED; RADIOIMMUNOASSAY; REFERENCE VALUES; SEX CHARACTERISTICS; TRANSCOBALAMINS; VITAMIN B 12;

EID: 0035736115     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/L6Q9-68E7-3284-6D1K     Document Type: Article

References (32)

1. 12-binding alpha globulin in two brothers. Blood. 1969;33:1-12.
2. Carmel R. R-binder deficiency: a clinically benign cause of cobalamin pseudodeficiency. JAMA. 1983;250:1886-1890.
3. Zittoun J, Leger J, Marquet J, et al. Combined congenital deficiencies of intrinsic factor and R binder. Blood. 1988;72:940-943.
4. Carmel R, Montes-Garces R, Wardinsky T, et al. Mild transcobalamin I deficiency is common and may be responsible for many low serum cobalamin levels: observations in a family and survey of 106 patients with low serum cobalamin levels not explained by malabsorption [abstract]. Biood 1996;88(suppl 1):646a.
5. Lin JC, Borregaard N, Liebman HA, et al. Deficiency of the specific granule proteins, R binder/transcobalamin I and lactoferrin, in plasma and saliva: a new disorder. Am J Med Genet. 2001;100:145-151.
6. 12 concentrations in leukaemia and in some other haematological conditions. Br J Haematol. 1955;1:155-72.
7. 12-binding proteins in chronic myeloproliferative disorders. Biol Clin Hematol. 1989;11:173-177.
8. Carmel R. Cobalamin-binding proteins in man. In: Silber R, Gordon AS, LoBue J, et al, eds. Contemporary Hematology-Oncology. Vol. 2. New York, NY: Plenum; 1981:79-129.
9. 12. J Clin Invest. 1975;56:1125-1131.
10. 12 in normal human serum. Clin Sci Mol Med. 1976;51:47-52.
11. 12 on the transcobalamins. Clin Sci Mol Med. 1977;52:215-218.
12. Nexo E, Andersen J. Unsaturated and cobalamin saturated transcobalamin I and II in normal human plasma. Scand J Clin Lab Invest. 1977;37:723-728.
13. 12 in normal human serum. Clin Sci Mol Med. 1977;53:453-457.
14. Carmel R. The distribution of endogenous cobalamin among cobalamin-binding proteins in the blood in normal and abnormal states. Am J Clin Nutr. 1985;41:713-719.
15. 12 binders in human serum. J Lab Clin Med. 1966;68:958-965.
16. 12-binding proteins in normal human blood plasma and serum. Scand J Haematol. 1972;9:639-647.
17. 12-binding proteins. Am J Clin Pathol. 1974;62:367-372.
18. 12 binders by instant batch separation using a microfine precipitate of silica (QUSO G32). J Lab Clin Med. 1975;86:505-512.
19. Lindemans J, Schoester M, van Kapel J. Application of a simple immunoadsorption assay for the measurement of saturated and unsaturated transcobalamin II and R-binders. Clin Chim Acta. 1983;132:53-61.
20. 12 in serum samples from healthy subjects and patients. J Clin Pathol. 1993;46:537-539.
21. 12-binding proteins in serum and plasma in various disorders: effect of anticoagulants. Am J Clin Pathol. 1978;69:319-325.
22. Birgens HS. Lactoferrin in plasma measured by an ELISA technique: evidence that plasma lactoferrin is an indicator of neutrophil turnover and bone marrow activity in acute leukaemias. Scand J Haematol. 1985;34:326-331.
23. Carmel R, Karnaze DS, Weiner JM. Neurological abnormalities in cobalamin deficiency are associated with higher cobalamin "analogue" values than are hematological abnormalities. J Lab Clin Med. 1988;111:57-62.
24. Cowland JB, Borregaard N. The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules. J Leukoc Biol. 1999;66:989-995.
25. Reitamo S, Konttinen YT, Segerberg-Konttinen M. Distribution of lactoferrin in human salivary glands. Histochemistry. 1980;66:285-291.
26. Levay PF, Viljoen M. Lactoferrin: a general review. Haematologia. 1995;80:252-267.
27. Bennett RM, Kokocinski T. Lactoferrin turnover in man. Clin Sci (Lond). 1979;57:453-460.
28. 12 bound to transcobalamin I and II. Scand J Haematol. 1967;4:321-332.
29. 12 bound in vitro and in vivo to transcobalamin I and II. Scand J Clin Lab Invest. 1969;23:201-211.
30. 12-binding capacity and transcobalamins in Nigerians and Europeans. Am J Clin Nutr. 1978;31:1732-1738.
31. Fernandes-Costa F, Metz J. A comparison of serum transcobalamin levels in white and black subjects. Am J Clin Nutr. 1982;35:83-86.
32. Carmel R. Ethnic and racial factors in cobalamin metabolism and its disorders. Semin Hematol. 1999;36:88-100.