Seasonal variations of T-cell cytokine pattern in peripheral blood from atopic subjects

Journal of Asthma

Volumn 38, Issue 6, 2001, Pages 469-476

  Majori, Maria ^a   Rossi, Gianluigi ^a   Caminati, Antonella ^a   Bosoni, Alessandra ^a   Corradi, Massimo ^a   Pesci, Alberto ^a  

^a Ist Clin Malattie Apparato Resp   (Italy)

Author keywords

Atopy; Peripheral blood T cells; TH2

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4;

ADULT; ARTICLE; ATOPY; BLOOD; CLINICAL ARTICLE; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; GRASS POLLEN; HELPER CELL; HUMAN; MALE; POLLEN ALLERGY; SEASONAL VARIATION; T LYMPHOCYTE SUBPOPULATION;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; MALE; RESPIRATORY HYPERSENSITIVITY; SEASONS;

EID: 0035735029     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.1081/JAS-100105867     Document Type: Article

References (32)

1. Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects
2. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma
3. Lol p I-induced IL-4 and IFN-y production by peripheral blood mononuclear cells of atopic and nonatopic subjects during and out of the pollen season
4. Seasonal variations of interleukin-4 and interferon-γ release by peripheral blood mononuclear cells from atopic subjects stimulated by polyclonal activators
5. Seasonal comparison of cytokine profiles in atopic asthmatics and atopic non-asthmatics
6. Seasonal rise in interleukin-4 during pollen season is related to seasonal rise in specific IgE for pollens but not for mites
7. Effect of seasonal exposure to pollen on nonspecific interleukin-4, interleukin-5, and interferon-gamma in vitro release by peripheral blood mononuclear cells from subjects with pollinosis
8. Seasonal variations in T-lymphocyte response to grass pollen allergens from pollen-allergic patients and healthy controls
9. Single IL-2-secreting precursor CD4 T-cell can develop into either Thl or Th2 cytokine secreting phenotype
10. Predominant Thl cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease
11. Detection of intracellular cytokines by flow cytometry
12. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
13. Effect of corticosteroids, cyclosporin A, and methotrexate on cytokine release from monocytes and T cell subsets
14. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry
15. Internalization, lysosomal degradation and new synthesis of surface membrane CD4 in phorbol ester-activated T-lymphocytes and U-937 cells
16. Decreased frequency of interferon-γ- and interleukin-2-producing cells in patients with atopic diseases measured at the single cell level
17. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
18. A subset of CD8+ T cells from allergic patients produce IL-4 and stimulate IgE production in vitro
19. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
20. In vivo effects of glucocorticoids on IgE production
21. CD4+, NK1.1+ T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
22. Interferon α increases the frequency of interferon γ-producing human CD4+ T cells
23. Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation
24. Dynamic T-cell changes in peripheral blood and bronchoalveolar lavage after antigen bronchoprovocation in asthmatics
25. Depletion of circulating allergen-specific Th2 T lymphocytes after allergen exposure in asthma
26. Intraepithelial dendritic cells and selective activation of TH2-like lymphocytes in patients with atopic asthma
27. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones
28. An alternative view of the Th1/Th2 switch hypothesis in HIV infection
29. Dutton reciprocal action of IL-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles
30. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting TH1 or TH2 cytokines
31. Virus specific CD8+ cells can switch to IL-5 production and induce airway eosinophilia
32. IL-4 is an essential cofactor for the IgE synthesis induced in vitro by human T cell clones and their supernatants