Hydroxyl radical scavenging and protective role of Tephrosia purpurea in gentamicin-induced kidney cell damage

Pharmaceutical Biology

Volumn 39, Issue 5, 2001, Pages 325-328

  Kumar, V Prashanth ^a   Shashidhara, S ^a   Kumar, M M ^a   Sridhara, B Y ^a  

^a B V PATEL PHARMACEUTICAL EDUCATION AND RESEARCH DEVELOPMENT PERD CENTRE   (India)

Author keywords

Cytoprotective; Gentamicin induced cell damage; Hydroxyl radical scavengers; Kidney cell damage; Tephrosia purpurea

Indexed keywords

ACID PHOSPHATASE; ALCOHOL DERIVATIVE; ANTIINFLAMMATORY AGENT; GENTAMICIN; HYDROXYL RADICAL; LACTATE DEHYDROGENASE; PLANT EXTRACT; SCAVENGER; TEPHROSIA PURPUREA EXTRACT; TRYPAN BLUE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME ASSAY; INDIA; KIDNEY CELL; KIDNEY CORTEX; KIDNEY INJURY; MALE; MEDICINAL PLANT; NONHUMAN; RAT; TEPHROSIA PURPUREA; TRADITIONAL MEDICINE;

ANIMALIA; LETHRINIDAE; TEPHROSIA; TEPHROSIA PURPUREA;

EID: 0035728724     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/phbi.39.5.325.5899     Document Type: Article

References (14)

1. Toxic nephropathies
2. Production of formaldehyde during metabolism of dimethylsulfoxide by hydroxyl radical generating systems
3. Estimation of proteins by Folin-Wu reagent
4. High yield method for kidney tissue culture
5. Mechanisms for protective effects of free radical scavengers on gentamicin-mediated nephropathy in rats
6. The colorimetric estimation of formaldehyde by means of Hantzch reaction
7. Effect of hydroxyl rutosides and related compounds on lipid peroxidation and free radical scavenging activity: Some structural aspects
8. Lactate dehydrogenase: UV-method with pyruvate and NADH
9. Gentamicin enhanced production of hydrogen peroxide by renal cortical mitochondria
10. Renal cortical mitochondria are the source of oxygen free radicals enhanced by gentamicin