Pharmacological properties of miglitol, an α-glucosidase inhibitor, in rats

Japanese Pharmacology and Therapeutics

Volumn 29, Issue 9, 2001, Pages 623-633

  Tsukamoto, Katsura ^a   Nakayama, Yukiharu ^a  

^a Central Research Laboratory   (Japan)

Author keywords

glucosidase; Inhibitor; Miglitol; Plasma glucose concentration

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; CARBOHYDRATE; GLUCOSE; MIGLITOL; STARCH; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCULATION; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; DOSE RESPONSE; DRUG POTENCY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; IN VIVO STUDY; INHIBITION KINETICS; INTESTINE ABSORPTION; LIPID ABSORPTION; NONHUMAN; POSTPRANDIAL STATE; RAT;

EID: 0035724334     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Effect of 1-desoxynojirimycin derivatives on small intestinal disaccharidase activities and on active transport in vitro
2. Inhibitory mechanism of acarbose and 1-deoxynojirimycin derivatives on carbohydrases in rat small intestine
3. Pharmacokinetics of miglitol. Absorption, distribution, metabolism, and excretion following administration to rats, dogs, and man
4. Effects of two α-glucosidase inhibitors, acarbose, and BAY- m-1099, on intestinal microflora, cecal properties, body-weight gains, serum cholesterol and serum lipids of rats
5. Über die Eigenschaften eines neuen chromogens für die blutzuckerbestimmung nach der GOD/POD-methode
6. Colorimetric method for determination of sugars and related substances
7. Improved method for enzymatic determination of serum triglycerides
8. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
9. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
10. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
11. 14C] acarbose to rats, dogs and man
12. Effect of miglitol administration to non-insulin-dependent diabetic rats
13. Inhibition of carbohydrate-induced hypertriglyceridemia by a disaccharidase inhibitor
14. Postprandial serum lipids and tissue lipoprotein lipase are acutely altered in rats by the α-glucosidase inhibitor acarbose
15. Inhibition of disaccharide digestion in rat intestine by the α-glucosidase inhibitor acarbose (BAY g 5421)