Kinetics and dose-response of photosensitivity in cream psoralen plus ultraviolet A photochemotherapy: Comparative in vivo studies after topical application of three standard preparations

British Journal of Dermatology

Volumn 144, Issue 5, 2001, Pages 991-995

  Connors, J B ^a   Rahil, A K ^b   Smith, F J D ^c   Mclean, W H I ^c   Milstone, L M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

8 methoxypsoralen; Cream psoralen plus ultraviolet A; Pharmacology; Photochemotherapy; Phototoxic response

Indexed keywords

DORITHIN; METHOXSALEN; OIL; WATER;

ADULT; AGED; ARTICLE; BIOLOGY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOSE CALCULATION; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; OINTMENT; PHOTOCHEMOTHERAPY; PHOTOSENSITIVITY; PHOTOTOXICITY; PRIORITY JOURNAL; PUVA; TOPICAL TREATMENT; ULTRAVIOLET A RADIATION;

ADMINISTRATION, CUTANEOUS; ADULT; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG CARRIERS; FEMALE; HUMANS; MALE; METHOXSALEN; MIDDLE AGED; PHOTOSENSITIZING AGENTS; PUVA THERAPY; SKIN DISEASES;

EID: 0035723908     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2001.04187.x     Document Type: Article

References (25)

1. Photochemotherapy and photodynamic therapy
2. Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA follow-up study
3. Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis
4. Treatment of psoriasis with trioxsalen baths and dysprosium lamps
5. Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis
6. Treatment of psoriasis with polyethylene sheet bath PUVA
7. Psoralen bath plus UV-A therapy. Possibilities and limitations
8. Topical methoxsalen and blacklight in the treatment of psoriasis
9. A new psoralen-containing gel for topical PUVA therapy: Development, and treatment results in patients with palmoplantar and plaque-type psoriasis, and hyperkeratotic eczema
10. Creme-PUVA-Photochemotherapie
11. Treatment of severe recalcitrant dermatoses of the palms and soles with PUVA-bath versus PUVA-cream therapy
12. PUVA-cream photochemotherapy for the treatment of localized scleroderma
13. High-performance liquid chromatographic measurement of 8-methoxypsoralen in plasma
14. Phototoxicity of topical trioxsalen
15. The time-course of psoralen ultraviolet A (PUVA) erythema
16. Assessment of minimal phototoxic dose following 8-methoxypsoralen bath: Maximal reaction on average after 5 days
17. Cream PUVA therapy for scleredema adultorum
18. The time course of phototoxicity of topical PUVA. 8-methoxypsoralen cream-PUVA vs. 8-methoxypsoralen gel-PUVA
19. Penetration, permeation, and resorption of 8-methoxypsoralen. Comparative in vitro and in vivo studies after topical application of four standard preparations
20. Long-term stability of 8-methoxypsoralen in ointments for topical PUVA therapy ('cream-PUVA')
21. Rapid decline in photosensitivity after 8-methoxypsoralen bathwater delivery
22. Time course of 8-MOP-induced skin photosensitization in PUVA bath photochemotherapy
23. Cancer incidence among Finnish patients with psoriasis treated with trioxsalen bath PUVA
24. Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report