Spatio-temporal expression of trefoil peptide following severe gastric ulceration in the rat implicates it in late-stage repair processes

Journal of Gastroenterology and Hepatology (Australia)

Volumn 16, Issue 5, 2001, Pages 506-512

  Ulaganathan, Meera ^a   Familari, Mary ^a   Yeomans, Neville D ^a   Giraud, Andrew S ^a   Cook, Gregory A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Gastric repair; Mucins; Trefoil factor 1; Trefoil peptide

Indexed keywords

ACETIC ACID; ALCIAN BLUE; CYCLINE; MESSENGER RNA; SCHIFF BASE; STOMACH MUCIN; TREFOIL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SECRETION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICROSCOPY; MUCOSA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; STAINING; STOMACH EPITHELIUM; STOMACH FUNDUS; STOMACH MUCOSA; STOMACH PH; STOMACH ULCER; ULCER HEALING;

EID: 0035719088     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2001.02469.x     Document Type: Article

References (37)

1. hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma
2. Breast cancer-associated pS2 protein: Synthesis and secretion by normal stomach mucosa
3. Identification of human intestinal trefoil factor
4. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells
5. Increased trefoil peptide expression occurs late in the healing phase in a model of gastric ulceration in rats
6. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach
7. Temporal expression of trefoil peptides in the TGF-alpha knockout mouse after gastric ulceration
8. Trefoil peptides promote epithelial migration through a transforming growth factor beta- independent pathway
9. Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration
10. Spasmolytic polypeptide is a major antral peptide: Distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach
11. Identification and characterisation of rat intestinal trefoil factor: Tissue and cell specific member of the trefoil protein family
12. Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa
13. pS2/TFF1 interacts directly with the VWFC cysteine-rich domain of mucins
14. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract
15. Combined intestinal trefoil factor and epidermal growth factor is prophylactic against indomethacin-induced gastric damage in the rat
16. Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats
17. Pancreatic spasmolytic polypeptide (PSP): Pharmacology of a new porcine pancreatic polypeptide with spasmolytic and gastric acid secretion inhibitory effects
18. Trefoil peptide protection of intestinal epithelial barrier function: Cooperative interaction with mucin glycoprotein
19. Human spasmolytic polypeptide decreases proton permeation through gastric mucus in-vivo and in-vitro
20. Pancreatic spasmolytic polypeptide: First three dimensional structure of a member of the mammalian trefoil family of peptides
21. Oral human spasmolytic polypeptide protects against aspirin-induced gastric injury in rats
22. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein
23. cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis
24. Coordinated expression of the three zona pellucida genes during mouse oogenesis
25. Vascular and microvascular changes - Key factors in the development of acetic acid induced ulcers in rats
26. Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells
27. Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss
28. Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Behaviour of entero-endocrine and caveolated cells: General conclusions on cell kinetics in the oxyntic epithelium
29. Trefoil peptides are early markers of gastrointestinal maturation in the rat
30. Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor alpha
31. DMBT1 encodes a protein involved in immune defense and in epithelial differentiation and is highly unstable in cancer
32. Isolation and characterization of putative trefoil peptide receptors
33. Etiology of gastric remnant cancer with special reference to the effects of denervation of the gastric mucosa
34. Importance of acidic mucin secretions by foveolar and mucus neck cell fundic mucosa as the defence mechanisms against HCl as revealed by fasting
35. Aspects of the biology of regeneration and repair in the human gastrointestinal tract
36. Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma
37. Expression of trefoil peptides in the gastric mucosa of transgenic mice overexpressing transforming growth factor alpha