Purification of a fragment of MDM2 for production of polyclonal antisera

Protein Expression and Purification

Volumn 21, Issue 2, 2001, Pages 361-365

  Carstens, Brian P ^a   Perry, Mary Ellen ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

EID: 0035718077     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1006/prep.2000.1386     Document Type: Article

References (14)

1. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
2. Repression of p53-mediated transcription by MDM2: A dual mechanism
3. Regulation of p53 stability by Mdm2
4. Mdm2 promotes the rapid degradation of p53
5. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
6. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
7. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
8. MDM2 to destabilize p53
9. Mapping of the p53 and MDM2 interaction domains
10. Unmasking of phosphorylation-sensitive epitopes on p53 and MDM2 by a simple Western procedure
11. Identifcation and characterization of multiple mdm-2 proteins and mdm-2-p53 complexes
12. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
13. Immunological evidence for the association of p53 with a heat shock protein, hsc 70, in p53-plus-ras-transformed cell lines
14. How to measure and predict the molar absorption coefficient of a protein