Embryonic exposure to lead: Comparison of immune and cellular responses in unchallenged and virally stressed chickens

Archives of Toxicology

Volumn 75, Issue 11, 2002, Pages 717-724

  Lee, Ji Eun ^a   Naqi, Syed A ^a   Kao, Elizabeth ^a   Dietert, Rodney R ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Delayed type hypersensitivity (DTH); IFN ; Infectious bronchitis virus; Lead; Leukocyte subpopulations; Production

Indexed keywords

BOVINE SERUM ALBUMIN; GAMMA INTERFERON; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; LEAD;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; AVIAN INFECTIOUS BRONCHITIS VIRUS; CELL POPULATION; CELLULAR IMMUNITY; CHICKEN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DEVELOPMENTAL STAGE; EGG; EMBRYO; EMBRYO DEVELOPMENT; EXPOSURE; IMMUNE RESPONSE; IMMUNOTOXICITY; INOCULATION; LEAD BLOOD LEVEL; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; STRESS; VIRUS INFECTION;

AVES; AVIAN INFECTIOUS BRONCHITIS VIRUS; BOVINAE; GALLUS GALLUS;

EID: 0035713847     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-001-0283-9     Document Type: Article

References (44)

1. Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation
2. Exposure to lead during critical windows of embryonic development: Differential immunotoxic outcome based on gender and stage of exposure
3. Persistent effect of in utero meso-2,3-dimercaptosuccinic acid (DMSA) on immune function and lead-induced immunotoxicity
4. The detection of cytotoxic lymphocyte activity in chickens infected with infectious bronchitis virus or fowl pox virus
5. The induction and control of delayed type hypersensitivity reactions induced in chickens by infectious bronchitis virus
6. Influence of lead and cadmium on the susceptibility of rats to bacterial challenge
7. Embryonic exposure to aflatoxin-B1: Mutagenicity and influence on development and immunity
8. Workshop to identify critical windows of exposure for children's health: Immune and respiratory systems work group summary
9. Serum immunoglobulin, complement C3, and salivary IgA levels in lead workers
10. Lead-cadmium interaction: Effects on viral-induced mortality and tissue residues in mice
11. Effects of combined pre- and postnatal lead exposure on cell mediated immune functions
12. + cells and functional impairments of lymphocytes at low-level occupational exposure to lead
13. Light microscopic and ultrastructural characterization of cells recovered by respiratory tract lavage of 2- and 6-week-old chickens
14. Activation of the Rauscher leukemia virus by metals
15. Lead aggravates viral disease and represses the antiviral activity of interferon inducers
16. Effects of heavy metals and of deficiency of zinc on mortality rates in mice infected with Encephalomyocarditis virus
17. The T-dependent immune system
18. Lead toxicity: Current concerns
19. 15N] nitrite in biological fluids
20. Lead suppression of mouse resistance to Salmonella typhimurium
21. Lead differentially modifies cytokine production in vitro and in vivo
22. Differential effect of lead and cAMP on development and activities of Th1- and Th2- lymphocytes
23. Development of the murine and human immune system: Differential effects of immunotoxicants depend on time of exposure
24. Immunotoxicology studies on lead: Effects of exposure on tumor growth and cell-mediated tumor immunity after syngeneic or allogeneic stimulation
25. Effects of lead oxide on the induction of lung tumors in Syrian hamsters
26. Early effects of lead on bone marrow cell responsiveness in mice challenged with Listeria monocytogenes
27. In vivo and in vitro effects of lead on humoral and cell-mediated immunity
28. Developmental windows of differential lead-induced immunotoxicity in chickens
29. Production of interferon-γ by chicken T cells
30. Depression of humoral immunity in rats following chronic developmental lead exposure
31. Lead
32. Lead, a major environmental pollutant, is immunomodulatory by its differential effects on CD4+ T cells subsets
33. Lead intoxication impairs the generation of a delayed type hypersensitivity response
34. Developmental exposure to lead causes persistent immunotoxicity in Fischer 344 rats
35. A rapid Zeeman graphite furnace atomic absorption spectrometric method for the determination of lead in blood
36. Changes in T cell subpopulations in lead workers
37. Effect of lead acetate on the susceptibility of rats to bacterial endotoxins
38. Systemic and local antibody responses to infectious bronchitis virus in chickens inoculated with infectious bursal disease virus and control chickens
39. Cytotoxic activity of cells recovered from the respiratory tracts of chickens inoculated with infectious bronchitis virus
40. Endotoxin studies in chicks: Effect of lead acetate
41. Immune alterations in lead-exposed workers
42. Effect of subclinical lead toxicity on the immune response of chickens to Newcastle disease virus vaccine
43. Immunomodulation by metals